Chlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates

Infect Immun. 1998 Dec;66(12):6017-21. doi: 10.1128/IAI.66.12.6017-6021.1998.


Chlamydia psittaci produces a collection of proteins, termed IncA, IncB, and IncC, that are localized to the chlamydial inclusion membrane. In this report we demonstrate that IncA is also produced by Chlamydia trachomatis. C. trachomatis IncA is structurally similar to C. psittaci IncA and is also localized to the inclusion membrane. Immunoblot analysis demonstrated that sera from C. trachomatis-infected patients and from experimentally infected monkeys both recognized C. trachomatis IncA.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Bacterial / blood*
  • Bacterial Proteins*
  • Cell Compartmentation
  • Chlamydia Infections / blood
  • Chlamydia trachomatis / immunology*
  • Chlamydophila psittaci
  • Humans
  • Macaca fascicularis
  • Membrane Proteins / immunology*
  • Membrane Proteins / isolation & purification
  • Phosphoproteins / immunology*
  • Phosphoproteins / isolation & purification
  • Sequence Homology, Amino Acid
  • Species Specificity


  • Antibodies, Bacterial
  • Bacterial Proteins
  • IncA protein, bacteria
  • Membrane Proteins
  • Phosphoproteins

Associated data

  • GENBANK/AF067958