Major depressive disorder in older adolescents: prevalence, risk factors, and clinical implications

Clin Psychol Rev. 1998 Nov;18(7):765-94. doi: 10.1016/s0272-7358(98)00010-5.


In this article we summarize our current understanding of depression in older (14-18 years old) adolescents based on our program of research (the Oregon Adolescent Depression Project). Specifically, we address the following factors regarding adolescent depression: (a) phenomenology (e.g., occurrence of specific symptoms, gender and age effects, community versus clinic samples); (b) epidemiology (e.g., prevalence, incidence, duration, onset age); (c) comorbidity with other mental and physical disorders; (d) psychosocial characteristics associated with being, becoming, and having been depressed; (e) recommended methods of assessment and screening; and (f) the efficacy of a treatment intervention developed for adolescent depression, the Adolescent Coping With Depression course. We conclude by providing a set of summary statements and recommendations for clinicians.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adaptation, Psychological
  • Adolescent
  • Age Distribution
  • Age of Onset
  • Comorbidity
  • Depressive Disorder / complications
  • Depressive Disorder / epidemiology*
  • Depressive Disorder / psychology*
  • Female
  • Humans
  • Male
  • Mental Disorders / complications
  • Prevalence
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Sex Distribution
  • Tobacco Use Disorder / complications