Clinical use of cisapride and its risk-benefit in paediatric patients

Eur J Gastroenterol Hepatol. 1998 Oct;10(10):871-81. doi: 10.1097/00042737-199810000-00011.


This paper provides a comprehensive review of the current knowledge on cisapride in different clinical conditions in children: different manifestations of gastro-oesophageal reflux, such as (excessive) regurgitation, oesophagitis, chronic respiratory disease or uncontrolled asthma, cystic fibrosis, chronic dyspepsia, constipation and pseudo-obstruction, and as an aid to small bowel capsule-biopsy. It discusses, in depth, the safety profile of cisapride in paediatric patients.

Publication types

  • Review

MeSH terms

  • Child
  • Child, Preschool
  • Cisapride / adverse effects
  • Cisapride / therapeutic use*
  • Constipation / drug therapy
  • Cystic Fibrosis / drug therapy
  • Drug Interactions
  • Dyspepsia / drug therapy
  • Fecal Incontinence / drug therapy
  • Gastroesophageal Reflux / drug therapy
  • Gastrointestinal Diseases / drug therapy*
  • Gastrointestinal Transit / drug effects
  • Humans
  • Infant
  • Intestinal Obstruction / drug therapy
  • Intestinal Pseudo-Obstruction / drug therapy
  • Risk Assessment


  • Cisapride