Midterm Clinical and Angiographic Results of Radial Artery Grafts Used for Myocardial Revascularization

J Thorac Cardiovasc Surg. 1998 Dec;116(6):1015-21. doi: 10.1016/S0022-5223(98)70054-6.

Abstract

Objective: To evaluate the midterm angiographic results of the use of radial artery grafts for myocardial revascularization.

Methods: The first 68 consecutive surviving patients who received a radial artery graft proximally anastomosed to the aorta at our institution were studied again at 5 years (mean 59 +/- 6.5 months) of follow-up; 48 of these patients had previously undergone an early angiographic examination. The response of the radial artery to the endovascular infusion of serotonin was evaluated 1 and 5 years after the operation, and the midterm status of the radial artery graft was correlated with the degree of preoperative stenosis of the target vessel and with calcium-channel blocker therapy.

Results: The patency and perfect patency rates of the radial artery grafts 5 years after the operation were 91.9% and 87.0%, respectively. All radial artery grafts that were patent early after the operation remained patent at midterm follow-up, and early parietal irregularities in 7 patients were seen to have disappeared after 5 years. The early propensity toward graft spasm after serotonin challenge was markedly decreased at midterm follow-up. The continued use of calcium-channel antagonists after the first postoperative year did not influence the radial artery graft status, whereas the preoperative severity of the target-vessel stenosis markedly influenced the angiographic results.

Conclusions: The midterm angiographic results of radial artery grafts used for myocardial revascularization are excellent. The correct surgical indication is essential. Continued therapy with calcium-channel antagonists after the first year does not influence the midterm angiographic results.

Publication types

  • Comparative Study

MeSH terms

  • Calcium Channel Blockers / therapeutic use
  • Coronary Angiography*
  • Coronary Artery Bypass
  • Coronary Disease / diagnostic imaging
  • Coronary Disease / drug therapy
  • Coronary Disease / surgery*
  • Female
  • Follow-Up Studies
  • Free Radical Scavengers / administration & dosage
  • Humans
  • Infusions, Intra-Arterial
  • Male
  • Middle Aged
  • Myocardial Revascularization* / methods
  • Radial Artery / diagnostic imaging
  • Radial Artery / drug effects
  • Radial Artery / transplantation*
  • Reoperation
  • Retrospective Studies
  • Serotonin / administration & dosage
  • Ultrasonography, Doppler
  • Vasoconstriction / drug effects

Substances

  • Calcium Channel Blockers
  • Free Radical Scavengers
  • Serotonin