Phosphorylcholine-coated metallic stents in rabbit iliac and porcine coronary arteries

Scand Cardiovasc J. 1998;32(5):261-8. doi: 10.1080/14017439850139843.

Abstract

The arterial wall reaction to phosphorylcholine-coated metal stents was examined in rabbits and pigs. Compared to non-coated stents, no significant difference was found by angiography and histology. We conclude that although phosphorylcholine-coating does not provoke arterial neointima formation or decrease luminal diameter compared to stainless steel stents, the coating does not seem to reduce restenosis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiography
  • Animals
  • Arteries / pathology*
  • Arteries / surgery*
  • Blood Vessel Prosthesis Implantation / instrumentation*
  • Blood Vessel Prosthesis Implantation / methods
  • Coated Materials, Biocompatible*
  • Coronary Angiography
  • Coronary Vessels / pathology
  • Coronary Vessels / surgery
  • Culture Techniques
  • Disease Models, Animal
  • Iliac Artery / diagnostic imaging
  • Iliac Artery / surgery
  • Male
  • Materials Testing
  • Metals
  • Phosphorylcholine* / chemistry
  • Rabbits
  • Reference Values
  • Stents*
  • Swine
  • Swine, Miniature

Substances

  • Coated Materials, Biocompatible
  • Metals
  • Phosphorylcholine