Androgens and fetal growth

Horm Res. 1998;50(4):243-4. doi: 10.1159/000023284.


Boys are heavier than girls at term birth. Children with a 46,XY karyotype and androgen insensitivity syndrome (clinically complete form and/or proven mutations in the androgen receptor gene) were found to have a birth weight comparable to that of girls. These findings support the hypothesis that the difference in birth weight between boys and girls is generated by androgen action.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Androgen-Insensitivity Syndrome / genetics
  • Androgen-Insensitivity Syndrome / physiopathology*
  • Androgens / physiology*
  • Birth Weight*
  • Embryonic and Fetal Development*
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Mutation
  • Receptors, Androgen / genetics
  • Sex Characteristics


  • Androgens
  • Receptors, Androgen