Colchicine in dermatology

J Am Acad Dermatol. 1998 Dec;39(6):993-9. doi: 10.1016/s0190-9622(98)70275-0.


Colchicine is a medication most often used to treat symptoms of gout. This drug has also been shown to have beneficial effects on cutaneous conditions, including leukocytoclastic vasculitis, psoriasis, and Sweet's syndrome. Colchicine inhibits the function of polymorphonuclear leukocytes, and dermatoses with a strong presence of these cells may benefit the most from the administration of this medication. A review of the pharmacology, mechanism of action, and adverse reactions of colchicine is also presented.

Publication types

  • Review

MeSH terms

  • Colchicine / adverse effects
  • Colchicine / pharmacology
  • Colchicine / therapeutic use*
  • Dermatologic Agents / adverse effects
  • Dermatologic Agents / pharmacology
  • Dermatologic Agents / therapeutic use*
  • Gout Suppressants / therapeutic use
  • Humans
  • Skin Diseases / drug therapy*


  • Dermatologic Agents
  • Gout Suppressants
  • Colchicine