Animal models for Porphyromonas gingivalis-mediated periodontal disease

Trends Microbiol. 1998 Nov;6(11):444-9. doi: 10.1016/s0966-842x(98)01363-8.


Porphyromonas gingivalis is one of the principal pathogens in the development of adult periodontitis. Several different animal models have been used to evaluate the complex interactions between P. gingivalis and the host and these have been an important research tool for studying the pathogenesis of P. gingivalis-mediated periodontal diseases.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Alveolar Bone Loss
  • Animals
  • Bacteroidaceae Infections* / physiopathology
  • Bacteroidaceae Infections* / therapy
  • Disease Models, Animal
  • Dogs
  • Humans
  • Periodontal Diseases* / physiopathology
  • Periodontal Diseases* / therapy
  • Periodontitis / complications
  • Porphyromonas gingivalis / physiology*
  • Primates