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. 1999 Jan 1;27(1):340-2.
doi: 10.1093/nar/27.1.340.

The Ligand Gated Ion Channel Database

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Free PMC article

The Ligand Gated Ion Channel Database

N Le Novère et al. Nucleic Acids Res. .
Free PMC article

Abstract

The ligand gated ion channels (LGICs) are ionotropic receptors to neurotransmitters. Their physiological effect is carried out by the opening of an ionic channel upon binding of a particular neurotransmitter. These LGICs constitute superfamilies of receptors formed by homologous subunits. A database has been developed to handle the growing wealth of cloned subunits. This database contains nucleic acid sequences, protein sequences, as well as multiple sequence alignments and phylogenetic studies. This database is accessible via the worldwide web (http://www.pasteur.fr/units/neubiomol/LGIC.h tml), where it is continuously updated. A downloadable version is also available [currently v0.1 (98.06)].

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