Favism by proxy in nursing glucose-6-phosphate dehydrogenase-deficient neonates

J Perinatol. Nov-Dec 1998;18(6 Pt 1):477-9.

Abstract

Two nursing neonates deficient in glucose-6-phosphate dehydrogenase developed severe hyperbilirubinemia despite phototherapy. Mothers of both the infants had recently eaten fava beans. The hemolytic triggers found in fava beans may have been absorbed by the mothers and excreted in their breast milk. Carboxyhemoglobin determination performed on one of the infants reflected ongoing hemolysis.

Publication types

  • Case Reports

MeSH terms

  • Breast Feeding*
  • Carboxyhemoglobin / analysis
  • Exchange Transfusion, Whole Blood
  • Fabaceae
  • Favism / complications*
  • Favism / etiology*
  • Female
  • Glucosephosphate Dehydrogenase Deficiency / complications
  • Hemolysis
  • Humans
  • Infant, Newborn
  • Jaundice, Neonatal / blood
  • Jaundice, Neonatal / etiology*
  • Jaundice, Neonatal / therapy
  • Male
  • Phototherapy
  • Plants, Medicinal

Substances

  • Carboxyhemoglobin