Atopic dermatitis apparently caused by type 2 CD8+ T cells in an AIDS patient

Clin Exp Dermatol. 1998 May;23(3):121-2. doi: 10.1046/j.1365-2230.1998.00340.x.

Abstract

A patient with atopic dermatitis and acquired immune deficiency syndrome (AIDS) had demonstrated blood eosinophilia, high levels of serum IgE and intracytoplasmic IL-4 in the CD8+ but not in the CD4+ cells, decreased numbers of CD4+ cells, and low levels of IL-2 in both CD4+ and CD8+ cells. These results, reflecting a predominant influence of type 2 CD8+ cells, suggest they were involved in the genesis exacerbation of the patient's atopic dermatitis.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • CD8-Positive T-Lymphocytes / immunology*
  • Dermatitis, Atopic / immunology*
  • Humans
  • Interleukin-2 / biosynthesis
  • Interleukin-4 / biosynthesis
  • Male
  • Middle Aged

Substances

  • Interleukin-2
  • Interleukin-4