Nineteen mothers of premature infants were interviewed in an attempt to determine a possible relationship between prematurity and orgasmic coitus during pregnancy. Although the limited number of subjects precludes tests of statistical significance and definite conclusions, the findings do suggest possible associations. While there appeared to be no relationship between prematurity and coitus per se during pregnancy, the association of frequent or intense orgasm with prematurity does raise some questions that further investigation might answer. Because of the hazard of prematurity to the subsequent development of the child, further exploration of the possible relationship of prematurity to orgasmic coitus during pregnancy appears warranted.