Malignancy-associated remission of systemic lupus erythematosus maintained by autologous peripheral blood stem cell transplantation

Arthritis Rheum. 1998 Dec;41(12):2271-2. doi: 10.1002/1529-0131(199812)41:12<2271::AID-ART25>3.0.CO;2-B.


Many investigators worldwide are currently exploring the role of peripheral blood stem cell transplantation (PBSCT) in managing autoimmune diseases. We report the case of a woman with systemic lupus erythematosus (SLE) with mucocutaneous and renal involvement, who underwent PBSCT for stage IVB Hodgkin's disease. Following the development of the lymphoma, she has had a prolonged clinical and serologic remission of the SLE. The potential effects of lymphoproliferative disorders and PBSCT on the course of SLE are considered.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Blood Transfusion, Autologous*
  • Female
  • Hematopoietic Stem Cell Transplantation*
  • Hodgkin Disease / complications*
  • Hodgkin Disease / therapy
  • Humans
  • Lupus Erythematosus, Systemic / complications*