Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease

Am J Cardiol. 1998 Dec 15;82(12):1535-9, A7-8. doi: 10.1016/s0002-9149(98)00702-4.


Previous studies showed a weak correlation between endothelial function of the coronary arteries as assessed by acetylcholine and brachial artery vasomotion during reactive hyperemia. When the same stimulus was used, we obtained a strong correlation between flow-mediated dilation in the coronary and brachial arteries (r=0.78, p <0.001), so that noninvasive assessment of flow-mediated dilation in the brachial artery could be used as a surrogate measure for coronary artery endothelial function.

MeSH terms

  • Adult
  • Aged
  • Brachial Artery / physiopathology*
  • Coronary Disease / physiopathology*
  • Coronary Vessels / physiopathology*
  • Endothelium, Vascular / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Vasodilation*