Effect of dopamine on renal blood flow of baboon in endotoxin shock

Pflugers Arch. 1978 Apr 25;374(1):105-6. doi: 10.1007/BF00585704.

Abstract

Renal vasodilation observed in canine endotoxemia did not occur during endotoxin shock in the baboon: in fact, renal artery blood flow was markedly reduced. Infusion of dopamine in the baboon restored the renal artery blood flow.

MeSH terms

  • Animals
  • Dopamine / therapeutic use*
  • Escherichia coli
  • Haplorhini
  • Kidney / blood supply*
  • Lipopolysaccharides
  • Papio
  • Regional Blood Flow
  • Shock, Septic / drug therapy*
  • Shock, Septic / physiopathology

Substances

  • Lipopolysaccharides
  • Dopamine