Abstract
Geraniol (1), olivetol (2), cannabinoids (3 and 4) and 5-fluorouracil (5) were tested for their growth inhibitory effects against human oral epitheloid carcinoma cell lines (KB) and NIH 3T3 fibroblasts using two different 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and sulforhodamine B protein (SRB) assay. Cannabigerol (3) exhibited the highest growth-inhibitory activity against the cancer cell lines.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology*
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Boranes
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Cannabinoids / chemistry
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Cannabinoids / isolation & purification
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Cannabinoids / pharmacology*
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Carcinoma / drug therapy*
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Cell Survival / drug effects
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Drug Screening Assays, Antitumor
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Humans
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Magnetic Resonance Spectroscopy
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Mouth Neoplasms / drug therapy*
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Nitroblue Tetrazolium
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Silicon Dioxide
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Spectrophotometry, Infrared
Substances
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Antineoplastic Agents, Phytogenic
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Boranes
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Cannabinoids
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Nitroblue Tetrazolium
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boron trifluoride etherate
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Silicon Dioxide
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cannabigerol