Fluoxetine as a treatment for post-stroke emotionalism

Acta Psychiatr Scand. 1998 Dec;98(6):455-8. doi: 10.1111/j.1600-0447.1998.tb10119.x.


The effectiveness of fluoxetine compared to placebo in the treatment of post-stroke emotionalism was investigated in 20 patients using a double-blind protocol. A total of 19 patients completed the study, as one subject in the treatment group had to be withdrawn. The subjects receiving fluoxetine showed a statistically and clinically significant improvement in their emotionalism compared to the placebo group, which was apparent in the majority of subjects from the third day of treatment.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Antidepressive Agents / therapeutic use*
  • Cerebral Infarction / psychology*
  • Double-Blind Method
  • Female
  • Fluoxetine / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Mood Disorders / drug therapy*
  • Mood Disorders / etiology*
  • Psychiatric Status Rating Scales
  • Severity of Illness Index


  • Antidepressive Agents
  • Fluoxetine