Automatic motion correction in dynamic radionuclide renography using image registration

Nucl Med Commun. 1998 Dec;19(12):1159-67. doi: 10.1097/00006231-199812000-00008.


Time-activity curves from dynamic renograms can be analysed to yield important quantitative parameters. However, accurate results are dependent on curves being free from artefacts caused by patient movement. We describe a method to correct for both translational and rotational motion during renography. The method is image-based and does not require markers. Sequential dynamic frames are registered using an affine transform from which rotational and translational components are extracted by singular-value decomposition. Computer simulations demonstrate correction to < 1 pixel and < 1 degree. The method is also fast, with renograms comprising 75 frames of 64 x 64 pixels taking under 1 min for correction on a Sun SPARC 5.

MeSH terms

  • Automation
  • Computer Simulation
  • Computing Methodologies
  • Humans
  • Image Processing, Computer-Assisted*
  • Kidney / diagnostic imaging*
  • Movement
  • Radioisotope Renography / methods*