Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production

Adv Exp Med Biol. 1998;454:203-17. doi: 10.1007/978-1-4615-4863-8_25.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aging
  • Animals
  • Cyclic GMP / metabolism
  • Gene Expression Regulation, Developmental
  • Gene Expression Regulation, Enzymologic
  • Heart / physiology
  • Heart / physiopathology*
  • Hypoxia / physiopathology*
  • In Vitro Techniques
  • Myocardial Ischemia / physiopathology*
  • Myocardial Reperfusion*
  • Myocardium / metabolism*
  • Nitrates / metabolism
  • Nitric Oxide / metabolism*
  • Nitric Oxide Synthase / genetics*
  • Nitric Oxide Synthase / metabolism
  • Nitrites / metabolism
  • Rabbits
  • Shock, Septic / metabolism
  • Shock, Septic / physiopathology*
  • Stress, Physiological / physiopathology
  • Transcription, Genetic
  • Ventricular Function, Left / physiology
  • Ventricular Function, Right / physiology

Substances

  • Nitrates
  • Nitrites
  • Nitric Oxide
  • Nitric Oxide Synthase
  • Cyclic GMP