Correlation of SPECT and PET cardiac images by a surface matching registration technique

Comput Med Imaging Graph. Sep-Oct 1998;22(5):391-8. doi: 10.1016/s0895-6111(98)00039-1.


Complementary information provided by Single Photon and Positron Emission Tomography (SPECT and PET) in nuclear cardiology allows a better comprehension of the physiopathology of the heart. In this work a surface matching registration technique is evaluated in the spatial correlation of SPECT and PET cardiac images. The method is based on matching correspondent anatomical surfaces extracted from transmission (TR) SPECT and PET studies, usually performed for attenuation correction. The accuracy of the technique was evaluated by phantom experiments and on patient data (201Tl SPECT and 13NH3 PET perfusion studies). An application of the method is presented for the correlation of SPECT 201Tl perfusion and PET 18FDG metabolic studies in the evaluation of myocardial viability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ammonia
  • Coronary Disease / diagnostic imaging
  • Evaluation Studies as Topic
  • Feasibility Studies
  • Female
  • Fluorodeoxyglucose F18
  • Glucose / metabolism
  • Heart / diagnostic imaging*
  • Humans
  • Image Enhancement
  • Image Processing, Computer-Assisted / methods*
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging
  • Myocardium / metabolism
  • Nitrogen Radioisotopes
  • Papillary Muscles / diagnostic imaging
  • Phantoms, Imaging
  • Radiopharmaceuticals
  • Regression Analysis
  • Reproducibility of Results
  • Thallium Radioisotopes
  • Tomography, Emission-Computed*
  • Tomography, Emission-Computed, Single-Photon*
  • Trachea / diagnostic imaging


  • Nitrogen Radioisotopes
  • Radiopharmaceuticals
  • Thallium Radioisotopes
  • Fluorodeoxyglucose F18
  • Ammonia
  • Glucose