Tubulin Structure: Insights Into Microtubule Properties and Functions

Curr Opin Struct Biol. 1998 Dec;8(6):785-91. doi: 10.1016/s0959-440x(98)80099-7.

Abstract

The structure of tubulin has recently been determined by electron crystallography, paving the way for a clearer understanding of the unique properties of tubulin that allow its varied functions within the cell. Some of the ongoing work on tubulin can be interpreted in terms of its structure, which can serve to guide future studies.

Publication types

  • Review

MeSH terms

  • Colchicine / metabolism
  • Microtubules / metabolism*
  • Models, Molecular
  • Paclitaxel / metabolism
  • Protein Conformation
  • Protein Folding
  • Tubulin / chemistry*
  • Tubulin / metabolism

Substances

  • Tubulin
  • Paclitaxel
  • Colchicine