Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis

Clin Orthop Relat Res. 1998 Oct;(355 Suppl):S257-66. doi: 10.1097/00003086-199810001-00026.


This review of 15 years research into various methods and techniques of using marrow osteoprogenitor cells shows that marrow grafts can be useful for numerous skeletal healing problems, but not all. The method offers considerable improvement over standard open iliac crest grafting and provides an attractive and advantageous method of stimulating osteogenesis in the management and prevention of nonunion.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Marrow Cells*
  • Bone Marrow Transplantation* / physiology
  • Fracture Healing
  • Fractures, Bone / surgery
  • Fractures, Ununited / prevention & control
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Ilium
  • Osteogenesis / physiology*
  • Transplantation, Autologous