Kinin receptors

Clin Rev Allergy Immunol. 1998 Winter;16(4):385-401. doi: 10.1007/BF02737658.


Rapid developments are expected in the molecular pharmacology of both B1, and B2 types of kinin receptors, since the underlying genetic structures are now known and widely studied. The consequences of kinin receptor duality and physiopathological regulation have not yet been fully appreciated. Medicinal chemistry is also an active front of research in kinin pharmacology, as more effective drugs targeted at kinin receptors are regularly reported. Various complementary molecular approaches (the receptor binding, cloning, immunoreacting, mutagenesis, inactivation, the study of regulation, allelic polymorphisms, and so forth) are expanding our knowledge of the role of kinins in allergy, inflammation, and singularly, renal medicine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Bradykinin / pharmacology
  • Bradykinin / physiology*
  • Bradykinin Receptor Antagonists
  • Gene Expression Regulation
  • Humans
  • Kinins / physiology*
  • Molecular Sequence Data
  • Receptors, Bradykinin* / chemistry
  • Receptors, Bradykinin* / genetics
  • Receptors, Bradykinin* / metabolism


  • Bradykinin Receptor Antagonists
  • Kinins
  • Receptors, Bradykinin
  • Bradykinin