Pilocarpine ocular inserts

Invest Ophthalmol. 1976 Dec;15(12):1008-10.


Pilocarpine was administered to a selected group of ocular hypertensive subjects in the form of a synthetic biosoluble matrix inserted into the conjunctival cul-de-sac. Satisfactory lowering of the intraocular pressure resulted, with a minimum of subject intolerance. The decreased pressure response was significant in some cases for greater than 24 hours. Drug delivery by soluble inserts offers promise as a convenient and effective mode of therapy.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Administration, Topical
  • Delayed-Action Preparations
  • Glaucoma / drug therapy*
  • Humans
  • Intraocular Pressure / drug effects
  • Pilocarpine / administration & dosage*
  • Pilocarpine / pharmacology
  • Pilocarpine / therapeutic use


  • Delayed-Action Preparations
  • Pilocarpine