Abstract
Truncated analogs of tripterine as cytokine (IL-1 alpha, IL-1 beta, TNF-alpha, IL-6, and IL-8) release inhibitors are discussed.
MeSH terms
-
Cells, Cultured
-
Humans
-
Interleukins / antagonists & inhibitors*
-
Interleukins / metabolism
-
Monocytes / drug effects
-
Monocytes / metabolism
-
Pentacyclic Triterpenes
-
Structure-Activity Relationship
-
Triterpenes / chemistry*
-
Triterpenes / pharmacology*
-
Tumor Necrosis Factor-alpha / antagonists & inhibitors*
-
Tumor Necrosis Factor-alpha / metabolism
Substances
-
Interleukins
-
Pentacyclic Triterpenes
-
Triterpenes
-
Tumor Necrosis Factor-alpha
-
celastrol