Abstract
Ficellomycin is a new basic antibiotic produced by Streptomyces ficellus. Ficellomycin, C13H24N6O3, inhibits the growth of gram-positive bacteria in vitro and is effective in the treatment of experimental Staphylococcus aureus infections in mice.
MeSH terms
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Animals
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Anti-Bacterial Agents / analysis
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Anti-Bacterial Agents / biosynthesis*
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Anti-Bacterial Agents / pharmacology
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Fermentation
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Lethal Dose 50
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Mice
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Peptide Biosynthesis
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Peptides / analysis
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Peptides / pharmacology
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Staphylococcal Infections / drug therapy
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Staphylococcus aureus / drug effects
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Streptomyces / metabolism*
Substances
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Anti-Bacterial Agents
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Peptides