Environmental pollution and the occurrence of congenital defects in a 15-year period in a south Moravian district

Acta Chir Plast. 1998;40(4):112-4.


We have made a simple 15-year retrospective epidemiological study of a part of South Moravia, district Breclav, on the basis of genetic documentation of 245 congenital defects and 28 spontaneous abortions. The whole area was worked up by computer-geographical methods, and the occurrence of congenital defects was compared both in areas of severe chronic air pollution and in less contamined areas. There were three municipal areas, Mikulov, Breclav-Postorná, Velké Bilovice and their surroundings, in which an increased number of congenital defects was recorded. In the municipal area of Breclav-Postorná there was also a greater occurrence of organic solvents and phosphoric acid and a significantly higher occurrence of spontaneous abortions and at the same time a higher occurrence of heart defects.

Publication types

  • Comparative Study

MeSH terms

  • Abortion, Spontaneous / epidemiology
  • Abortion, Spontaneous / genetics
  • Air Pollutants / analysis
  • Air Pollution / analysis
  • Air Pollution / statistics & numerical data*
  • Congenital Abnormalities / epidemiology*
  • Congenital Abnormalities / genetics
  • Czech Republic / epidemiology
  • Dust / analysis
  • Female
  • Heart Defects, Congenital / epidemiology
  • Humans
  • Infant
  • Phosphoric Acids / analysis
  • Pregnancy
  • Retrospective Studies
  • Solvents / analysis
  • Sulfur Dioxide / analysis
  • Urban Health / statistics & numerical data


  • Air Pollutants
  • Dust
  • Phosphoric Acids
  • Solvents
  • Sulfur Dioxide