[Biological markers of schizophrenic symptoms: functional neuroimaging]

Actas Luso Esp Neurol Psiquiatr Cienc Afines. Sep-Oct 1998;26(5):309-14.
[Article in Spanish]


Despite heterogeneous phenotype, lack of pathognomonic symptoms and great variability of symptoms during the course of the illness, functional neuroimaging studies have showed specific patterns of activation associated to particular schizophrenic symptoms or symptom dimensions. Negative symptoms have been associated to hypofrontality; auditory hallucinations seem to be related to abnormalities in brain regions involved in language and, reality distortion dimension has been associated to left temporal lobe impairments.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers
  • Brain / diagnostic imaging*
  • Humans
  • Regional Blood Flow
  • Schizophrenia / diagnosis*
  • Schizophrenic Psychology
  • Temporal Lobe / blood supply
  • Tomography, X-Ray Computed


  • Biomarkers