Skin closures using cyanoacrylate tissue adhesives. Plastic Surgery Educational Foundation DATA Committee. Device and Technique Assessment

Plast Reconstr Surg. 1999 Feb;103(2):730-1. doi: 10.1097/00006534-199902000-00061.


Studies have been done and approval is soon possible from the FDA for an octylcyanoacrylate tissue glue for closure of lacerations of incisions. This is a newer-generation cyanoacrylate that improves on the butylcyanoacrylates currently in use in Canada and other countries but not approved by the FDA. It is a pliable, waterproof, film adhesive that can be applied to a laceration and left in place until it disintegrates in 7 to 14 days. It is safe and effective and represents an improvement over the butylcyanoacrylates that have been used for years in many countries. It is not a replacement for sutures but does offer an alternative. Some indications that seem appropriate are for closure of incisions that would be under casts; for simple lacerations in children to avoid the fear of suturing and suture removal; and for closure of incisions or lacerations where it would be a problem for a follow-up visit. This adhesive is less indicated for closure over highly mobile areas such as joints; for areas with usage and friction such as hands or feet; or for areas where exact alignment is a priority, such as the face or eyelids.

MeSH terms

  • Cyanoacrylates / therapeutic use*
  • Dermatologic Surgical Procedures
  • Humans
  • Wounds and Injuries / therapy*


  • Cyanoacrylates