Jumping translocation of 1q as the sole aberration in a case of follicular lymphoma

Cancer Genet Cytogenet. 1999 Jan 1;108(1):53-6. doi: 10.1016/s0165-4608(98)00111-3.

Abstract

Cytogenetic and fluorescence in situ hybridization (FISH) studies in a case of follicular lymphoma grade III showed a "jumping translocation" of chromosome 1q21-qter to chromosomes Xq28 and 18q23, which resulted in a partial trisomy 1q as the only chromosome aberration. This case represents, to the best of our knowledge, the first report of a jumping translocation in a malignant lymphoma occurring as the sole aberration.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 1*
  • Chromosomes, Human, Pair 18*
  • Female
  • Humans
  • In Situ Hybridization, Fluorescence
  • Karyotyping
  • Lymph Nodes / pathology
  • Lymphoma, Follicular / genetics*
  • Lymphoma, Follicular / pathology
  • Middle Aged
  • Translocation, Genetic*
  • Tumor Cells, Cultured
  • X Chromosome*