Karyotype evolution in a case of uterine angioleiomyoma

Cancer Genet Cytogenet. 1999 Jan 1;108(1):79-80. doi: 10.1016/s0165-4608(98)00123-x.


Clonal karyotypic alterations of a uterine angioleiomyoma of a 41-year-old woman are reported. Cytogenetically a stemline of the tumor and two related subclones with additional abnormalities due to karyotypic evolution were identified: 46,X,t(X;11)(p11.4;p15)/46, idem,inv(2)(p15q13)/46, idem,inv(2)(p15q13),t(5;20)(q13;q13.2). None of the aberrations observed in the present case has been reported in uterine smooth muscle tumors before.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiomyoma / genetics*
  • Angiomyoma / pathology
  • Angiomyoma / surgery
  • Chromosome Inversion
  • Chromosome Mapping
  • Chromosomes, Human, Pair 11*
  • Female
  • Humans
  • Karyotyping
  • Translocation, Genetic*
  • Uterine Neoplasms / genetics*
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / surgery
  • X Chromosome*