Current trends in the detection of antigenaemia, metabolites and cell wall markers for the diagnosis and therapeutic monitoring of fungal infections

P E Verweij; D Poulain; T Obayashi; T F Patterson; D W Denning; J Ponton

Current trends in the detection of antigenaemia, metabolites and cell wall markers for the diagnosis and therapeutic monitoring of fungal infections

Med Mycol. 1998:36 Suppl 1:146-55.

Authors

P E Verweij¹, D Poulain, T Obayashi, T F Patterson, D W Denning, J Ponton

Affiliation

¹ Department of Medical Microbiology, University Hospital Nijmegen, The Netherlands.

PMID: 9988503

Abstract

There have been several recent developments in the diagnosis of fungal infections, including the production of novel antigen detection tests, the G-test, and assays for the detection of fungal metabolites. In this article we present an overview of these developments and examine the value of including these tests in clinical trials.

Publication types

Review

MeSH terms

Antigens, Fungal / blood*
Antigens, Fungal / immunology
Aspergillosis / diagnosis*
Candidiasis / diagnosis*
Clinical Trials as Topic
Enzyme-Linked Immunosorbent Assay / methods
Female
Glucans / blood
Glucans / immunology
Humans
Immunologic Tests / methods*
Latex Fixation Tests / methods
Male
Mannans / blood
Mannans / immunology
Mycoses / diagnosis*

Substances

Antigens, Fungal
Glucans
Mannans