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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 4
1980 7
1981 16
1982 18
1983 23
1984 16
1985 18
1986 18
1987 16
1988 14
1989 14
1990 13
1991 21
1992 29
1993 26
1994 40
1995 37
1996 60
1997 60
1998 76
1999 74
2000 75
2001 50
2002 82
2003 99
2004 87
2005 102
2006 77
2007 53
2008 58
2009 66
2010 96
2011 86
2012 111
2013 119
2014 151
2015 161
2016 185
2017 237
2018 194
2019 257
2020 301
2021 360
2022 389
2023 391
2024 391
2025 4

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4,282 results

Results by year

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Page 1
Hypoglycemia post bariatric surgery: drugs with different mechanisms of action to treat a unique disorder.
Carpentieri GB, Gonçalves SEAB, Mourad WM, Pinto LGC, Zanella MT. Carpentieri GB, et al. Arch Endocrinol Metab. 2023 Mar 30;67(3):442-449. doi: 10.20945/2359-3997000000598. Epub 2023 Feb 7. Arch Endocrinol Metab. 2023. PMID: 36748934 Free PMC article. Review.
In this review, we gathered articles on PPH after BS from PubMed searches (2001 to 2022) and focused on the main drugs tested for the treatment of this condition, such as acarbose, somatostatin analogues, type 2 sodium-glucose cotransporter inhibitors, calcium channel bloc …
In this review, we gathered articles on PPH after BS from PubMed searches (2001 to 2022) and focused on the main drugs tested for the treatm …
Acarbose enhances the efficacy of immunotherapy against solid tumours by modulating the gut microbiota.
Zhang SL, Wang X, Cai QQ, Chen C, Zhang ZY, Xu YY, Yang MX, Jia QA, Wang Y, Wang ZM. Zhang SL, et al. Nat Metab. 2024 Oct;6(10):1991-2009. doi: 10.1038/s42255-024-01137-1. Epub 2024 Sep 25. Nat Metab. 2024. PMID: 39322747
Here we show that oral administration of acarbose significantly increases the anti-tumour response to anti-PD-1 therapy in female tumour-bearing mice. ...The bacterial species Bifidobacterium infantis, which is enriched by acarbose, also improves response to anti-PD …
Here we show that oral administration of acarbose significantly increases the anti-tumour response to anti-PD-1 therapy in female tum …
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome.
Bitto A, Grillo AS, Ito TK, Stanaway IB, Nguyen BMG, Ying K, Tung H, Smith K, Tran N, Velikanje G, Urfer SR, Snyder JM, Barton J, Sharma A, Kayser EB, Wang L, Smith DL Jr, Thompson JW, DuBois L, DePaolo W, Kaeberlein M. Bitto A, et al. Nat Metab. 2023 Jun;5(6):955-967. doi: 10.1038/s42255-023-00815-w. Epub 2023 Jun 26. Nat Metab. 2023. PMID: 37365290
Unlike rapamycin, acarbose rescues disease phenotypes independently of inhibition of the mechanistic target of rapamycin. ...We find that acarbose remodels the intestinal microbiome and alters the production of short-chain fatty acids. ...
Unlike rapamycin, acarbose rescues disease phenotypes independently of inhibition of the mechanistic target of rapamycin. ...We find …
The biosynthesis of acarbose and validamycin.
Mahmud T, Lee S, Floss HG. Mahmud T, et al. Chem Rec. 2001;1(4):300-10. doi: 10.1002/tcr.1015. Chem Rec. 2001. PMID: 11893070 Review.
The deoxyhexose moiety of acarbose arises from glucose with deoxythymidyl-diphospho-4-keto-6-deoxy-D-glucose (dTDP-4-keto-6-deoxy-D-glucose) as a proximate intermediate. However, despite the identical origin of the aminocyclitol moieties in acarbose and validamycin …
The deoxyhexose moiety of acarbose arises from glucose with deoxythymidyl-diphospho-4-keto-6-deoxy-D-glucose (dTDP-4-keto-6-deoxy-D-g …
[Biosynthesis and regulatory mechanism of acarbose and its structural analogs: a review].
Wang Y, Dai K, Xie K, Weng C. Wang Y, et al. Sheng Wu Gong Cheng Xue Bao. 2022 Feb 25;38(2):605-619. doi: 10.13345/j.cjb.210248. Sheng Wu Gong Cheng Xue Bao. 2022. PMID: 35234385 Free article. Review. Chinese.
Acarbose is widely used as alpha-glucosidase inhibitor in the treatment of type diabetes. Actinoplanes sp. is used for industrial production of acarbose. As a secondary metabolite, the biosynthesis of acarbose is quite complex. In addition to acarbose, …
Acarbose is widely used as alpha-glucosidase inhibitor in the treatment of type diabetes. Actinoplanes sp. is used for industrial pro …
Alpha glucosidase inhibitors.
Kalra S. Kalra S. J Pak Med Assoc. 2014 Apr;64(4):474-6. J Pak Med Assoc. 2014. PMID: 24864650
Important Aspects of Post-Prandial Antidiabetic Drug, Acarbose.
Singla RK, Singh R, Dubey AK. Singla RK, et al. Curr Top Med Chem. 2016;16(23):2625-33. doi: 10.2174/1568026616666160414123500. Curr Top Med Chem. 2016. PMID: 27086787 Review.
Acarbose, a well known and efficacious alpha-amylase and alpha-glucosidase inhibitor, is a postprandial acting antidiabetic drug. DNS-based alpha-amylase inhibitory assays showed that use of acarbose at concentrations above 125 g/ml resulted in release of reducing s …
Acarbose, a well known and efficacious alpha-amylase and alpha-glucosidase inhibitor, is a postprandial acting antidiabetic drug. DNS …
The human microbiome encodes resistance to the antidiabetic drug acarbose.
Balaich J, Estrella M, Wu G, Jeffrey PD, Biswas A, Zhao L, Korennykh A, Donia MS. Balaich J, et al. Nature. 2021 Dec;600(7887):110-115. doi: 10.1038/s41586-021-04091-0. Epub 2021 Nov 24. Nature. 2021. PMID: 34819672 Free PMC article.
Here, using a metagenomics-based search strategy, we discovered that bacterial members of the human gut and oral microbiome encode enzymes that selectively phosphorylate a clinically used antidiabetic drug, acarbose(1,2), resulting in its inactivation. Acarbose is a …
Here, using a metagenomics-based search strategy, we discovered that bacterial members of the human gut and oral microbiome encode enzymes t …
Healthy Aging Interventions Reduce Repetitive Element Transcripts.
Wahl D, Cavalier AN, Smith M, Seals DR, LaRocca TJ. Wahl D, et al. J Gerontol A Biol Sci Med Sci. 2021 Apr 30;76(5):805-810. doi: 10.1093/gerona/glaa302. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33257951 Free PMC article.
Here, we analyze REs in RNA-seq datasets from mice subjected to robust healthspan- and lifespan-increasing interventions including calorie restriction, rapamycin, acarbose, 17-alpha-estradiol, and Protandim. We also examine RE transcripts in long-lived transgenic mice, and …
Here, we analyze REs in RNA-seq datasets from mice subjected to robust healthspan- and lifespan-increasing interventions including calorie r …
4,282 results