Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1964 3
1965 4
1966 3
1967 1
1968 5
1969 2
1970 10
1971 5
1972 10
1973 6
1974 3
1975 8
1976 8
1977 4
1978 5
1979 7
1980 9
1981 13
1982 9
1983 9
1984 10
1985 15
1986 11
1987 8
1988 8
1989 16
1990 8
1991 14
1992 9
1993 7
1994 9
1995 18
1996 19
1997 24
1998 23
1999 20
2000 15
2001 29
2002 18
2003 16
2004 23
2005 31
2006 28
2007 26
2008 26
2009 26
2010 35
2011 44
2012 45
2013 45
2014 48
2015 44
2016 55
2017 61
2018 58
2019 73
2020 55
2021 57
2022 63
2023 67
2024 70
2025 61

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

1,307 results

Results by year

Filters applied: . Clear all
Page 1
Caffeine, but not paracetamol (acetaminophen), enhances muscular endurance, strength, and power.
Scapec B, Grgic J, Varovic D, Mikulic P. Scapec B, et al. J Int Soc Sports Nutr. 2024 Dec;21(1):2400513. doi: 10.1080/15502783.2024.2400513. Epub 2024 Sep 8. J Int Soc Sports Nutr. 2024. PMID: 39246027 Free PMC article. Clinical Trial.
BACKGROUND: Caffeine is one of the most popular ergogenic aids consumed by athletes. Caffeine's ergogenic effect has been generally explained by its ability to bind to adenosine receptors, thus modulating pain and reducing perceived exertion. Another pharmaco …
BACKGROUND: Caffeine is one of the most popular ergogenic aids consumed by athletes. Caffeine's ergogenic effect has be …
In Utero Exposure to Caffeine and Acetaminophen, the Gut Microbiome, and Neurodevelopmental Outcomes: A Prospective Birth Cohort Study.
Laue HE, Shen Y, Bloomquist TR, Wu H, Brennan KJM, Cassoulet R, Wilkie E, Gillet V, Desautels AS, Abdelouahab N, Bellenger JP, Burris HH, Coull BA, Weisskopf MG, Zhang W, Takser L, Baccarelli AA. Laue HE, et al. Int J Environ Res Public Health. 2022 Jul 30;19(15):9357. doi: 10.3390/ijerph19159357. Int J Environ Res Public Health. 2022. PMID: 35954712 Free PMC article.
Pregnant individuals are exposed to acetaminophen and caffeine, but it is unknown how these exposures interact with the developing gut microbiome. We aimed to determine whether acetaminophen and/or caffeine relate to the childhood gut microbiome and wh …
Pregnant individuals are exposed to acetaminophen and caffeine, but it is unknown how these exposures interact with the develo …
Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics.
Gonçalves DF, de Carvalho NR, Leite MB, Courtes AA, Hartmann DD, Stefanello ST, da Silva IK, Franco JL, Soares FAA, Dalla Corte CL. Gonçalves DF, et al. Life Sci. 2018 Jan 15;193:234-241. doi: 10.1016/j.lfs.2017.10.039. Epub 2017 Oct 28. Life Sci. 2018. PMID: 29107792 Free article.
AIMS: Many studies have been demonstrating the role of mitochondrial function in acetaminophen (APAP) hepatotoxicity. Since APAP is commonly consumed with caffeine, this work evaluated the effects of the combination of APAP and caffeine on hepatic mitochondri …
AIMS: Many studies have been demonstrating the role of mitochondrial function in acetaminophen (APAP) hepatotoxicity. Since APAP is c …
The Prophylactic Effect of Acetaminophen and Caffeine on Post Dural Puncture Headache after Spinal Anesthesia for Cesarean Section: A Randomized Double-Blind Clinical Trial.
Hadavi SMR, Panah A, Shamohammadi S, Kanaani Nejad F, Sahmeddini MA, Asmarian N. Hadavi SMR, et al. Iran J Med Sci. 2024 Sep 1;49(9):573-579. doi: 10.30476/ijms.2023.99577.3166. eCollection 2024 Sep. Iran J Med Sci. 2024. PMID: 39371383 Free PMC article. Clinical Trial.
The purpose of this study was to evaluate the effectiveness of acetaminophen and caffeine in preventing PDPH. METHODS: This double-blind, randomized clinical trial was conducted on 96 obstetric women, who were candidates for elective cesarean section. ...CONCLUSION: …
The purpose of this study was to evaluate the effectiveness of acetaminophen and caffeine in preventing PDPH. METHODS: This do …
Combination analgesics.
Beaver WT. Beaver WT. Am J Med. 1984 Sep 10;77(3A):38-53. doi: 10.1016/s0002-9343(84)80101-1. Am J Med. 1984. PMID: 6486130
Six rationales for using combination analgesics are identified, but most combinations are formulated with two rationales in mind: enhancement of analgesia and reduction of adverse effects by combining two analgesics with different mechanisms of action. Acetaminophen and as …
Six rationales for using combination analgesics are identified, but most combinations are formulated with two rationales in mind: enhancemen …
Competitive adsorption of acetaminophen and caffeine onto activated Tingui biochar: characterization, modeling, and mechanisms.
Dos Santos DF, Moreira WM, de Araújo TP, Bernardo MMS, de Figueiredo Ligeiro da Fonseca IM, Ostroski IC, de Barros MASD. Dos Santos DF, et al. Environ Sci Pollut Res Int. 2024 Sep;31(41):53611-53628. doi: 10.1007/s11356-023-31024-3. Epub 2023 Nov 27. Environ Sci Pollut Res Int. 2024. PMID: 38008834
The monocomponent adsorption equilibrium was reached in 90 min with a maximum adsorption capacity of 424.7 and 350.8 mg g(-1) for acetaminophen and caffeine, respectively. For the bicomponent solution adsorption, the maximum adsorption capacity was 199.4 and 297.5 m …
The monocomponent adsorption equilibrium was reached in 90 min with a maximum adsorption capacity of 424.7 and 350.8 mg g(-1) for acetami …
Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials.
Diener HC, Gaul C, Lehmacher W, Weiser T. Diener HC, et al. Eur J Neurol. 2022 Jan;29(1):350-357. doi: 10.1111/ene.15103. Epub 2021 Sep 28. Eur J Neurol. 2022. PMID: 34519136
BACKGROUND AND PURPOSE: Many migraine patients rely on over-the-counter analgesics for the treatment of migraine attacks. Fixed-dose combinations of aspirin, paracetamol and caffeine (APC) have been used for treating migraine in many countries for a long time. ...
BACKGROUND AND PURPOSE: Many migraine patients rely on over-the-counter analgesics for the treatment of migraine attacks. Fixed-dose combina …
Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates acetaminophen toxicity in human fetal immortalized hepatocytes.
Viswanathan P, Gupta P, Sharma Y, Maisuradze L, Bandi S, Gupta S. Viswanathan P, et al. Toxicology. 2021 Jun 15;457:152811. doi: 10.1016/j.tox.2021.152811. Epub 2021 May 7. Toxicology. 2021. PMID: 33971260
Caffeine markedly exacerbated acetaminophen toxicity by suppressing ATM activity in otherwise nontoxic 2.5 millimolar amount. ...Synergistic caffeine and acetaminophen toxicity in liver organoids indicated these consequences should apply in vivo. ...
Caffeine markedly exacerbated acetaminophen toxicity by suppressing ATM activity in otherwise nontoxic 2.5 millimolar amount. …
A safety assessment of fixed combinations of acetaminophen and acetylsalicylic acid, coformulated with caffeine.
Bach PH, Berndt WO, Delzell E, Dubach U, Finn WF, Fox JM, Hess R, Michielsen P, Sandler DP, Trump B, Williams G. Bach PH, et al. Ren Fail. 1998 Nov;20(6):749-62. doi: 10.3109/08860229809045173. Ren Fail. 1998. PMID: 9834974 Free article. Review.
There is a rational basis for coformulating acetylsalicylic acid (ASA) and acetaminophen (paracetamol) as this reduces the dose of each, without altering efficacy. The coformulation of caffeine with these analgesics has a significant adjuvant effect and incre …
There is a rational basis for coformulating acetylsalicylic acid (ASA) and acetaminophen (paracetamol) as this reduces the dos …
Photocatalytic degradation of acetaminophen and caffeine using magnetite-hematite combined nanoparticles: kinetics and mechanisms.
Fernandes TA, Mendo SG, Ferreira LP, Neng NR, Oliveira MC, Gil A, Carvalho MD, Monteiro OC, Nogueira JMF, Calhorda MJ. Fernandes TA, et al. Environ Sci Pollut Res Int. 2021 Apr;28(14):17228-17243. doi: 10.1007/s11356-020-12016-z. Epub 2021 Jan 4. Environ Sci Pollut Res Int. 2021. PMID: 33394452
The increased use of pharmaceutical and personal care products (PPCPs) has contributed to the contamination of water systems and put pressure on the development of new techniques to deal with this problem. Acetaminophen (paracetamol), a common analgesic and antipyre …
The increased use of pharmaceutical and personal care products (PPCPs) has contributed to the contamination of water systems and put pressur …
1,307 results