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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 4
1966 10
1967 8
1968 6
1969 8
1970 14
1971 4
1972 12
1973 13
1974 26
1975 22
1976 31
1977 20
1978 18
1979 20
1980 18
1981 19
1982 27
1983 35
1984 43
1985 38
1986 41
1987 40
1988 36
1989 37
1990 59
1991 62
1992 60
1993 71
1994 70
1995 72
1996 90
1997 98
1998 79
1999 91
2000 88
2001 99
2002 84
2003 122
2004 110
2005 134
2006 145
2007 147
2008 115
2009 137
2010 151
2011 168
2012 149
2013 161
2014 157
2015 151
2016 149
2017 176
2018 177
2019 171
2020 165
2021 162
2022 128
2023 25
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Search Results

4,170 results
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Page 1
Ibuprofen versus paracetamol for treating fever in preschool children in Nigeria: a randomized clinical trial of effectiveness and safety.
Alaje EO, Udoh EE, Akande PA, Odey FA, Meremikwu MM. Alaje EO, et al. Pan Afr Med J. 2020 Aug 26;36:350. doi: 10.11604/pamj.2020.36.350.21393. eCollection 2020. Pan Afr Med J. 2020. PMID: 33224416 Free PMC article. Clinical Trial.
The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and paracetamol in treating fever in under-fives were conducted in Europe and North America with very few in African children. ...RESULTS: the …
The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and pa …
Pharmacokinetics and Bioavailability of a Fixed-Dose Combination of Ibuprofen and Paracetamol after Intravenous and Oral Administration.
Atkinson HC, Stanescu I, Frampton C, Salem II, Beasley CP, Robson R. Atkinson HC, et al. Clin Drug Investig. 2015 Oct;35(10):625-32. doi: 10.1007/s40261-015-0320-8. Clin Drug Investig. 2015. PMID: 26334726 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: Previously published studies have suggested the lack of a pharmacokinetic interaction between ibuprofen and paracetamol when they are delivered as a fixed-dose oral combination. ...CONCLUSION: Concomitant administration of 3 mg/mL ibuprofen and 1 …
BACKGROUND AND OBJECTIVES: Previously published studies have suggested the lack of a pharmacokinetic interaction between ibuprofen and pa …
Bioavailable turmeric extract for knee osteoarthritis: a randomized, non-inferiority trial versus paracetamol.
Singhal S, Hasan N, Nirmal K, Chawla R, Chawla S, Kalra BS, Dhal A. Singhal S, et al. Trials. 2021 Jan 30;22(1):105. doi: 10.1186/s13063-021-05053-7. Trials. 2021. PMID: 33516238 Free PMC article. Clinical Trial.
BACKGROUND: To compare the efficacy and safety of bioavailable turmeric extract versus paracetamol in patients with knee osteoarthritis (OA). METHODS: In this randomized, non-inferiority, controlled clinical study, patients of knee OA were randomized to receive bioavailabl …
BACKGROUND: To compare the efficacy and safety of bioavailable turmeric extract versus paracetamol in patients with knee osteoarthrit …
Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study.
Lyngstad G, Skjelbred P, Swanson DM, Skoglund LA. Lyngstad G, et al. Eur J Clin Pharmacol. 2021 Dec;77(12):1843-1852. doi: 10.1007/s00228-021-03231-9. Epub 2021 Oct 16. Eur J Clin Pharmacol. 2021. PMID: 34655316 Free PMC article. Clinical Trial.
PURPOSE: Effect size estimates of analgesic drugs can be misleading. Ibuprofen (400 mg, 600 mg, 800 mg), paracetamol (1000 mg, 500 mg), paracetamol 1000 mg/codeine 60 mg, and placebo were investigated to establish the multidimensional pharmacodynamic profiles of eac …
PURPOSE: Effect size estimates of analgesic drugs can be misleading. Ibuprofen (400 mg, 600 mg, 800 mg), paracetamol (1000 mg, 500 mg …
An open label randomized clinical trial of Indomethacin for mild and moderate hospitalised Covid-19 patients.
Ravichandran R, Mohan SK, Sukumaran SK, Kamaraj D, Daivasuga SS, Ravi SOAS, Vijayaraghavalu S, Kumar RK. Ravichandran R, et al. Sci Rep. 2022 Apr 19;12(1):6413. doi: 10.1038/s41598-022-10370-1. Sci Rep. 2022. PMID: 35440611 Free PMC article. Clinical Trial.
In the indomethacin group, none of the 103 patients developed desaturation. On the other hand, 20 of the 107 patients in the paracetamol arm developed desaturation. Patients who received indomethacin also experienced more rapid symptomatic relief than those in the parac …
In the indomethacin group, none of the 103 patients developed desaturation. On the other hand, 20 of the 107 patients in the paracetamol …
Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial.
Hay AD, Costelloe C, Redmond NM, Montgomery AA, Fletcher M, Hollinghurst S, Peters TJ. Hay AD, et al. BMJ. 2008 Sep 2;337:a1302. doi: 10.1136/bmj.a1302. BMJ. 2008. PMID: 18765450 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate whether paracetamol (acetaminophen) plus ibuprofen are superior to either drug alone for increasing time without fever and the relief of fever associated discomfort in febrile children managed at home. ...For less time with fever over 24 ho …
OBJECTIVE: To investigate whether paracetamol (acetaminophen) plus ibuprofen are superior to either drug alone for increasing …
Comparison of intravenous ibuprofen and paracetamol in the treatment of fever: A randomized double-blind study.
Can Ö, Kıyan GS, Yalçınlı S. Can Ö, et al. Am J Emerg Med. 2021 Aug;46:102-106. doi: 10.1016/j.ajem.2021.02.057. Epub 2021 Mar 3. Am J Emerg Med. 2021. PMID: 33740568 Clinical Trial.
Studies comparing oral forms of non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol with intravenous (IV) forms for fever are common in the literature. ...They can be effectively used as each other's rescue medicine and as an alternative to each other in …
Studies comparing oral forms of non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol with intravenous (IV) forms for fever …
From painkiller to empathy killer: acetaminophen (paracetamol) reduces empathy for pain.
Mischkowski D, Crocker J, Way BM. Mischkowski D, et al. Soc Cogn Affect Neurosci. 2016 Sep;11(9):1345-53. doi: 10.1093/scan/nsw057. Epub 2016 May 5. Soc Cogn Affect Neurosci. 2016. PMID: 27217114 Free PMC article. Clinical Trial.
Here, we extend the functional overlap perspective to the neurochemical level and test whether a common physical painkiller, acetaminophen (paracetamol), can reduce empathy for another's pain. In two double-blind placebo-controlled experiments, participants r …
Here, we extend the functional overlap perspective to the neurochemical level and test whether a common physical painkiller, acetaminophe …
Acetaminophen.
Ameer B, Greenblatt DJ. Ameer B, et al. Ann Intern Med. 1977 Aug;87(2):202-9. doi: 10.7326/0003-4819-87-2-202. Ann Intern Med. 1977. PMID: 329728 Review.
Acetaminophen is an effective mild analgesic and antipyretic agent. In double-blind, controlled experimental pain studies of short duration, acetaminophen is superior to placebo and produces analgesia comparable to that produced by aspirin. The frequency of adverse …
Acetaminophen is an effective mild analgesic and antipyretic agent. In double-blind, controlled experimental pain studies of short du …
Efficacy and safety of oral paracetamol versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants: a randomized controlled trial.
El-Farrash RA, El Shimy MS, El-Sakka AS, Ahmed MG, Abdel-Moez DG. El-Farrash RA, et al. J Matern Fetal Neonatal Med. 2019 Nov;32(21):3647-3654. doi: 10.1080/14767058.2018.1470235. Epub 2018 May 9. J Matern Fetal Neonatal Med. 2019. PMID: 29695206 Clinical Trial.
Neonates were randomly assigned to two groups: 30 received oral ibuprofen and 30 received oral paracetamol. With failure of ductal closure, a second course of ibuprofen or paracetamol was given. ...Conclusions: Oral paracetamol is an effective and well-tolera …
Neonates were randomly assigned to two groups: 30 received oral ibuprofen and 30 received oral paracetamol. With failure of ductal cl …
4,170 results