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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 4
1966 10
1967 8
1968 6
1969 8
1970 14
1971 4
1972 12
1973 13
1974 26
1975 22
1976 31
1977 20
1978 18
1979 20
1980 18
1981 19
1982 27
1983 35
1984 43
1985 38
1986 41
1987 40
1988 36
1989 37
1990 59
1991 62
1992 60
1993 71
1994 70
1995 72
1996 90
1997 98
1998 79
1999 91
2000 88
2001 99
2002 84
2003 122
2004 110
2005 134
2006 145
2007 147
2008 115
2009 137
2010 151
2011 168
2012 149
2013 161
2014 156
2015 151
2016 149
2017 175
2018 177
2019 169
2020 162
2021 163
2022 134
2023 96
2024 106
2025 96
2026 25

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4,430 results

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Page 1
Ibuprofen versus paracetamol for treating fever in preschool children in Nigeria: a randomized clinical trial of effectiveness and safety.
Alaje EO, Udoh EE, Akande PA, Odey FA, Meremikwu MM. Alaje EO, et al. Pan Afr Med J. 2020 Aug 26;36:350. doi: 10.11604/pamj.2020.36.350.21393. eCollection 2020. Pan Afr Med J. 2020. PMID: 33224416 Free PMC article. Clinical Trial.
The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and paracetamol in treating fever in under-fives were conducted in Europe and North America with very few in African children. ...RESULTS: the …
The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and pa …
Bioavailable turmeric extract for knee osteoarthritis: a randomized, non-inferiority trial versus paracetamol.
Singhal S, Hasan N, Nirmal K, Chawla R, Chawla S, Kalra BS, Dhal A. Singhal S, et al. Trials. 2021 Jan 30;22(1):105. doi: 10.1186/s13063-021-05053-7. Trials. 2021. PMID: 33516238 Free PMC article. Clinical Trial.
BACKGROUND: To compare the efficacy and safety of bioavailable turmeric extract versus paracetamol in patients with knee osteoarthritis (OA). METHODS: In this randomized, non-inferiority, controlled clinical study, patients of knee OA were randomized to receive bioavailabl …
BACKGROUND: To compare the efficacy and safety of bioavailable turmeric extract versus paracetamol in patients with knee osteoarthrit …
Caffeine, but not paracetamol (acetaminophen), enhances muscular endurance, strength, and power.
Scapec B, Grgic J, Varovic D, Mikulic P. Scapec B, et al. J Int Soc Sports Nutr. 2024 Dec;21(1):2400513. doi: 10.1080/15502783.2024.2400513. Epub 2024 Sep 8. J Int Soc Sports Nutr. 2024. PMID: 39246027 Free PMC article. Clinical Trial.
Another pharmacological agent that may improve performance due to its analgesic proprieties is paracetamol. This study aimed to explore the effects of caffeine, paracetamol, and caffeine + paracetamol consumption on muscular endurance, strength, power, anaero …
Another pharmacological agent that may improve performance due to its analgesic proprieties is paracetamol. This study aimed to explo …
Pharmacokinetics and Bioavailability of a Fixed-Dose Combination of Ibuprofen and Paracetamol after Intravenous and Oral Administration.
Atkinson HC, Stanescu I, Frampton C, Salem II, Beasley CP, Robson R. Atkinson HC, et al. Clin Drug Investig. 2015 Oct;35(10):625-32. doi: 10.1007/s40261-015-0320-8. Clin Drug Investig. 2015. PMID: 26334726 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: Previously published studies have suggested the lack of a pharmacokinetic interaction between ibuprofen and paracetamol when they are delivered as a fixed-dose oral combination. The aim of this study was to determine the pharmacokinetic profile a …
BACKGROUND AND OBJECTIVES: Previously published studies have suggested the lack of a pharmacokinetic interaction between ibuprofen and pa …
Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study.
Lyngstad G, Skjelbred P, Swanson DM, Skoglund LA. Lyngstad G, et al. Eur J Clin Pharmacol. 2021 Dec;77(12):1843-1852. doi: 10.1007/s00228-021-03231-9. Epub 2021 Oct 16. Eur J Clin Pharmacol. 2021. PMID: 34655316 Free PMC article. Clinical Trial.
PURPOSE: Effect size estimates of analgesic drugs can be misleading. Ibuprofen (400 mg, 600 mg, 800 mg), paracetamol (1000 mg, 500 mg), paracetamol 1000 mg/codeine 60 mg, and placebo were investigated to establish the multidimensional pharmacodynamic profiles of eac …
PURPOSE: Effect size estimates of analgesic drugs can be misleading. Ibuprofen (400 mg, 600 mg, 800 mg), paracetamol (1000 mg, 500 mg …
Effect of a Single Preventive Intravenous Dose of Ketorolac and Paracetamol on Reducing Postoperative Pain in Septorhinoplasty Patients: Double-Blind Randomized Clinical Trial.
Dehghanpisheh L, Jamshidi F, Khademi S, Farokhiani S, Cheraghi MR, Emadi M, Kaboodkhani R, Akbari A, Asmarian N, Banifatemi M. Dehghanpisheh L, et al. Iran J Med Sci. 2025 Apr 1;50(4):239-246. doi: 10.30476/ijms.2024.102131.3488. eCollection 2025 Apr. Iran J Med Sci. 2025. PMID: 40255229 Free PMC article. Clinical Trial.
RESULTS: One-hour post-surgery, VAS scores in the ketorolac and paracetamol groups were significantly lower than in the placebo group (P<0.001). The mean difference with 95% CI for ketorolac-placebo and paracetamol-placebo was -0.57 (-0.94, -0.21), and -0.79 (-1. …
RESULTS: One-hour post-surgery, VAS scores in the ketorolac and paracetamol groups were significantly lower than in the placebo group …
Effects of acetaminophen on risk taking.
Keaveney A, Peters E, Way B. Keaveney A, et al. Soc Cogn Affect Neurosci. 2020 Sep 24;15(7):725-732. doi: 10.1093/scan/nsaa108. Soc Cogn Affect Neurosci. 2020. PMID: 32888031 Free PMC article. Clinical Trial.
Recent research has suggested that acetaminophen's effects extend to the blunting of negative as well as positive affect. Because affect is a determinant of risk perception and risk taking, we tested the hypothesis that acute acetaminophen consumption (1000 m …
Recent research has suggested that acetaminophen's effects extend to the blunting of negative as well as positive affect. Beca …
Comparative Effectiveness of Paracetamol, Ibuprofen, and their Combination in Managing Post-Endodontic Treatment Pain.
Otakhoigbogie U, Onyia NE, Omogbai EKI, Sede MA. Otakhoigbogie U, et al. West Afr J Med. 2024 Nov 29;41(11):1129-1136. West Afr J Med. 2024. PMID: 40231775 Clinical Trial.
Non-opioid analgesics like non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol, have been used with great success in treating patients with endodontic pain. ...CONCLUSION: Paracetamol significantly reduced post-endodontic pain better than ibuprofen and it …
Non-opioid analgesics like non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol, have been used with great success in treat …
Randomized open-label non-inferiority trial of paracetamol or celecoxib for patients with chronic low back pain.
Hayashi K, Miki K, Ueno H, Sekiguchi M, Arai YC, Nikaido T, Shiga Y, Inoue M, Kataoka H, Kawarai Y, Kimura Y, Shimizu K, Shimo K, Shiro Y, Tanaka K, Tanaka S, Hirakawa Y, Miura K, Yukioka M. Hayashi K, et al. Sci Rep. 2025 Dec 9;16(1):1577. doi: 10.1038/s41598-025-31094-y. Sci Rep. 2025. PMID: 41366055 Free PMC article. Clinical Trial.
This randomized controlled study aimed to compare the analgesic effects of paracetamol and celecoxib in a non-inferiority trial. This non-inferiority trial tested the hypothesis that paracetamol is as effective as celecoxib for the treatment of CLBP within a pre-spe …
This randomized controlled study aimed to compare the analgesic effects of paracetamol and celecoxib in a non-inferiority trial. This …
Evaluation of the relationship between effervescent paracetamol and blood pressure: clinical trial.
Benitez-Camps M, Vinyoles-Bargalló E, Rebagliato-Nadal O, Morros-Pedrós R, Pera-Pujadas H, Dalfó-Baqué A, López-Pavón I, Roca-Sánchez C, Coma-Carbó RM, De La Figuera Von Wichmann M, Mengual-Martínez L, Yuste-Marco C, Teixidó-Colet M, Pepió i Vilaubí JM, Ciurana-Tost R, Pou-Vila R, Vila-Coll MA, Bordas-Julve JM, Aragonès-Forès R, Pelegrina-Rodríguez FJ, Agudo-Ugena J, Blanco-Mata C, de la Iglesia Berrojalbiz J, Burgos-Alonso N, Gómez-Fernández MC. Benitez-Camps M, et al. BMC Cardiovasc Disord. 2015 Dec 10;15:167. doi: 10.1186/s12872-015-0161-7. BMC Cardiovasc Disord. 2015. PMID: 26654907 Free PMC article. Clinical Trial.
BACKGROUND: Paracetamol's solubility is achieved by adding to the excipient sodium salts, either as bicarbonate, carbonate or citrate. ...Therefore, the objective of this study is to evaluate the effect on blood pressure of effervescent paracetamol compared t …
BACKGROUND: Paracetamol's solubility is achieved by adding to the excipient sodium salts, either as bicarbonate, carbonate or …
4,430 results