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Development and validation of a generic high-performance liquid chromatography for the simultaneous separation and determination of six cough ingredients: Robustness study on core-shell particles.
Yehia AM, Essam HM. Yehia AM, et al. J Sep Sci. 2016 Sep;39(17):3357-67. doi: 10.1002/jssc.201600438. Epub 2016 Aug 11. J Sep Sci. 2016. PMID: 27404374
A generally applicable high-performance liquid chromatographic method for the qualitative and quantitative determination of pharmaceutical preparations containing phenylephrine hydrochloride, paracetamol, ephedrine hydrochloride, guaifenesin, doxylamine succi …
A generally applicable high-performance liquid chromatographic method for the qualitative and quantitative determination of pharmaceutical p …
Trends in US Pediatric Unintentional Nonprescription Cold and Cough, Analgesic and Antipyretic Drug Exposure Cases amid the COVID-19 Pandemic.
Karami S, Ventura CAI, Pinnow E, Green J, Asonye A, Ibrahim IT, McCulley L, Dal Pan GJ, Zhou EH. Karami S, et al. Clin Drug Investig. 2025 Jul;45(7):401-416. doi: 10.1007/s40261-025-01444-9. Epub 2025 May 28. Clin Drug Investig. 2025. PMID: 40434620 Free PMC article.
OBJECTIVE: We assessed monthly unintentional pediatric (< 18 years) exposure case rate trends involving selected nonprescription cold and cough (CC), as well as analgesic and antipyretic (AA) drugs, before and during the COVID-19 pandemic, using the National Poison Data System …
OBJECTIVE: We assessed monthly unintentional pediatric (< 18 years) exposure case rate trends involving selected nonprescription cold and …
Rapid screening and multicomponent quantifications of active components of oral syrup over-the-counter medications by Raman and UV-visible spectroscopy and multivariate regression analysis.
Fakayode SO, Bolton B, Dassow B, Galvez K, Chohan H. Fakayode SO, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jan 15;305:123447. doi: 10.1016/j.saa.2023.123447. Epub 2023 Sep 21. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 37742594
PLS regressions of UV-visible absorption spectra were used for multicomponent quantifications of the active component (acetaminophen, guaifenesin, dextromethorphan HBr, and phenylephrine HCl) concentrations of OTMCs in flavored (sugar or sugar-free) or …
PLS regressions of UV-visible absorption spectra were used for multicomponent quantifications of the active component (acetaminophen, …
Development and validation of a generic RP-HPLC PDA method for the simultaneous separation and quantification of active ingredients in cold and cough medicines.
Dongala T, Katari NK, Palakurthi AK, Jonnalagadda SB. Dongala T, et al. Biomed Chromatogr. 2019 Nov;33(11):e4641. doi: 10.1002/bmc.4641. Epub 2019 Aug 8. Biomed Chromatogr. 2019. PMID: 31265736
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determination of seven pharmaceutically active ingredients, namely, acetaminophen, dextromethorphan, doxylamine, phenylephrine, …
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determinat …
Anaphylaxis to dextromethorphan with positive skin testing: a case report.
Badawod E, Campbell J, Lee E. Badawod E, et al. Allergy Asthma Clin Immunol. 2025 Oct 31;21(1):46. doi: 10.1186/s13223-025-00987-y. Allergy Asthma Clin Immunol. 2025. PMID: 41174719 Free PMC article.
BACKGROUND: Dextromethorphan (DM) is a cough suppressant that is widely available in many prescribed and over-the-counter medications. ...The patient experienced a severe allergic reaction after taking Vicks Dayquil Complete , a common over-the-counter cold and flu medicin …
BACKGROUND: Dextromethorphan (DM) is a cough suppressant that is widely available in many prescribed and over-the-counter medications …
Intentional pediatric nonprescription cold/cough and analgesic/antipyretic exposure trends amid the COVID-19 pandemic.
Karami S, Ventura CAI, Pinnow E, Ibrahim I, Chang D, Asonye A, McCulley L, Meyer T, Dal Pan GJ, Zhou EH. Karami S, et al. Clin Toxicol (Phila). 2026 Jun;64(6):503-515. doi: 10.1080/15563650.2026.2621059. Epub 2026 Feb 18. Clin Toxicol (Phila). 2026. PMID: 41705545 Free PMC article.
METHODS: Using descriptive and interrupted time-series analyses, we assessed monthly pediatric (6-17 years) exposure case rates involving nonprescription analgesic/antipyretic drugs containing paracetamol (acetaminophen), ibuprofen, acetylsalicylic acid, and naproxe …
METHODS: Using descriptive and interrupted time-series analyses, we assessed monthly pediatric (6-17 years) exposure case rates involving no …
Ion mobility spectrometry for the rapid analysis of over-the-counter drugs and beverages.
Fernández-Maestre R, Hill HH. Fernández-Maestre R, et al. Int J Ion Mobil Spectrom. 2009 Aug;12(3):91-102. doi: 10.1007/s12127-009-0025-x. Epub 2009 Jul 1. Int J Ion Mobil Spectrom. 2009. PMID: 20835390 Free PMC article.
The active ingredients determined in drugs were acetaminophen, aspartame, bisacodyl, caffeine, dextromethorphan, diphenhydramine, famotidine, glucosamine, guaifenesin, loratadine, niacin, phenylephrine, pyridoxine, thiamin, and tetrahydrozoline. ...
The active ingredients determined in drugs were acetaminophen, aspartame, bisacodyl, caffeine, dextromethorphan, diphenhydrami …