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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
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1986 1
1988 1
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1992 1
1993 3
1995 2
1996 4
1997 1
1999 1
2001 1
2002 1
2003 1
2005 1
2006 1
2007 1
2008 1
2010 1
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2012 1
2015 1
2017 3
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38 results

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Page 1
Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department.
Meyering SH, Stringer RW, Hysell MK. Meyering SH, et al. West J Emerg Med. 2017 Apr;18(3):373-381. doi: 10.5811/westjem.2016.12.29218. Epub 2017 Feb 27. West J Emerg Med. 2017. PMID: 28435487 Free PMC article. Clinical Trial.
Secondary outcomes measures included assessment of decreased requirement of "rescue" pain medicines, defined as any analgesic medications outside of diphenhydramine, prochlorperazine and acetaminophen, with particular interest to potential opioid-sparing effects wit …
Secondary outcomes measures included assessment of decreased requirement of "rescue" pain medicines, defined as any analgesic medications ou …
Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial.
Pourfakhr P, Aghabagheri M, Zabihi Mahmoudabadi H, Najjari K, Talebpour M, Khajavi MR. Pourfakhr P, et al. Obes Surg. 2021 Oct;31(10):4371-4375. doi: 10.1007/s11695-021-05589-2. Epub 2021 Jul 27. Obes Surg. 2021. PMID: 34313917 Clinical Trial.
This study investigated the effect of adding diphenhydramine to acetaminophen and ondansetron in reducing postoperative nausea and vomiting and pain following laparoscopic sleeve gastrectomy (LSG). MATERIALS AND METHODS: Eighty-two patients scheduled for LSG were as …
This study investigated the effect of adding diphenhydramine to acetaminophen and ondansetron in reducing postoperative nausea …
Acetaminophen and diphenhydramine as premedication for platelet transfusions: a prospective randomized double-blind placebo-controlled trial.
Wang SE, Lara PN Jr, Lee-Ow A, Reed J, Wang LR, Palmer P, Tuscano JM, Richman CM, Beckett L, Wun T. Wang SE, et al. Am J Hematol. 2002 Jul;70(3):191-4. doi: 10.1002/ajh.10119. Am J Hematol. 2002. PMID: 12111764 Free article. Clinical Trial.
Non-hemolytic transfusion reactions (NHTR) occur in up to 30% of patients receiving platelet transfusions. Premedication with acetaminophen and diphenhydramine is a common strategy to prevent NHTR, but its efficacy has not been studied. In this prospective trial, tr …
Non-hemolytic transfusion reactions (NHTR) occur in up to 30% of patients receiving platelet transfusions. Premedication with acetaminoph …
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
Kennedy LD, Case LD, Hurd DD, Cruz JM, Pomper GJ. Kennedy LD, et al. Transfusion. 2008 Nov;48(11):2285-91. doi: 10.1111/j.1537-2995.2008.01858.x. Epub 2008 Jul 30. Transfusion. 2008. PMID: 18673350 Clinical Trial.
BACKGROUND: Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions. ...Patients were excluded if they had a known allergy to either acetaminophen or diphenhydramine or had a documented history …
BACKGROUND: Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions …
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study).
Childress KMS, Dothager C, Gavard JA, Lebovitz S, Laska C, Mostello DJ. Childress KMS, et al. Am J Perinatol. 2018 Nov;35(13):1281-1286. doi: 10.1055/s-0038-1646952. Epub 2018 May 3. Am J Perinatol. 2018. PMID: 29723901 Clinical Trial.
OBJECTIVE: We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison. ...CONCLUSION: MAD effectively relieves headaches in pregnant women w …
OBJECTIVE: We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when …
Prospective surveillance of intravenous amphotericin B use patterns.
Grasela TH Jr, Goodwin SD, Walawander MK, Cramer RL, Fuhs DW, Moriarty VP. Grasela TH Jr, et al. Pharmacotherapy. 1990;10(5):341-8. Pharmacotherapy. 1990. PMID: 2235670 Review.
A wide variety of pretreatment medications were used to minimize IRAE; the most common regimens included some combination of diphenhydramine, acetaminophen, and corticosteroids, with or without heparin. The majority of patients (84.7%) received a test dose, and alth …
A wide variety of pretreatment medications were used to minimize IRAE; the most common regimens included some combination of diphenhydram …
Prophylactic administration of diphenhydramine/paracetamol reduced emergence agitation and postoperative pain following maxillofacial surgeries: a randomized controlled trial.
Khajavi MR, Saffarian A, Majidi F, Moharari RS, Pourfakhr P, Parhiz SA. Khajavi MR, et al. Eur Arch Otorhinolaryngol. 2022 Mar;279(3):1467-1471. doi: 10.1007/s00405-021-06904-4. Epub 2021 May 27. Eur Arch Otorhinolaryngol. 2022. PMID: 34043064 Clinical Trial.
METHODS: Eighty-five patients undergoing maxillofacial surgery were randomized into two groups. The diphenhydramine group (Group D, n = 40) received diphenhydramine premedication 0.5 mg/kg before anesthesia induction, while the control group (Group C, n = 40) receiv …
METHODS: Eighty-five patients undergoing maxillofacial surgery were randomized into two groups. The diphenhydramine group (Group D, n …
Clinical efficacy of antihistaminics as analgesics.
Rumore MM, Schlichting DA. Rumore MM, et al. Pain. 1986 Apr;25(1):7-22. doi: 10.1016/0304-3959(86)90004-7. Pain. 1986. PMID: 2872645 Clinical Trial.
The evidence indicates a direct analgesic effect of various antihistaminics. In clinical studies, diphenhydramine, hydroxyzine, orphenadrine and pyrilamine have been shown to produce analgesia as simple entities but chlorpheniramine has not and results with phenyltoloxamin …
The evidence indicates a direct analgesic effect of various antihistaminics. In clinical studies, diphenhydramine, hydroxyzine, orphe …
Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease.
Cobleigh MA, Vogel CL, Tripathy D, Robert NJ, Scholl S, Fehrenbacher L, Wolter JM, Paton V, Shak S, Lieberman G, Slamon DJ. Cobleigh MA, et al. J Clin Oncol. 2023 Mar 10;41(8):1501-1510. doi: 10.1200/JCO.22.02510. J Clin Oncol. 2023. PMID: 36881998 Clinical Trial.
These symptoms were treated successfully with acetaminophen and/or diphenhydramine. The most clinically significant adverse event was cardiac dysfunction, which occurred in 4.7% of patients. ...
These symptoms were treated successfully with acetaminophen and/or diphenhydramine. The most clinically significant adverse ev …
Pediatric Tape: Accuracy and Medication Delivery in the National Park Service.
Campagne DD, Young M, Wheeler J, Stroh G. Campagne DD, et al. West J Emerg Med. 2015 Sep;16(5):665-70. doi: 10.5811/westjem.2015.6.25618. Epub 2015 Oct 20. West J Emerg Med. 2015. PMID: 26587088 Free PMC article. Clinical Trial.
Each scenario required dosing two medications (Case 1 [febrile seizure] required midazolam and acetaminophen; Case 2 [anaphylactic reaction] required epinephrine and diphenhydramine). Twenty NPS EMS providers, trained at the Parkmedic/Advanced Emergency Medical Tech …
Each scenario required dosing two medications (Case 1 [febrile seizure] required midazolam and acetaminophen; Case 2 [anaphylactic re …
38 results