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Bioavailability of paracetamol, phenylephrine hydrochloride and guaifenesin in a fixed-combination syrup versus an oral reference product.
Janin A, Monnet J. Janin A, et al. J Int Med Res. 2014 Apr;42(2):347-59. doi: 10.1177/0300060513503762. Epub 2014 Feb 19. J Int Med Res. 2014. PMID: 24553480 Free article. Clinical Trial.
OBJECTIVES: The primary objective of this study was to compare the bioavailability of paracetamol, phenylephrine hydrochloride and guaifenesin in a new oral syrup with an established oral reference product. ...Blood samples were taken regularly postdose and a …
OBJECTIVES: The primary objective of this study was to compare the bioavailability of paracetamol, phenylephrine hydrochloride …
An open-label, randomized, four-treatment crossover study evaluating the effects of salt form, acetaminophen, and food on the pharmacokinetics of phenylephrine.
Gelotte CK. Gelotte CK. Regul Toxicol Pharmacol. 2018 Jun;95:333-338. doi: 10.1016/j.yrtph.2018.04.008. Epub 2018 Apr 7. Regul Toxicol Pharmacol. 2018. PMID: 29635061 Free article. Clinical Trial.
Test treatments were 25 mg phenylephrine tannate (equivalent to 10 mg phenylephrine HCl) combined with 200 mg guaifenesin, fasted; 10 mg phenylephrine HCl combined with 650 mg acetaminophen, fasted; and 10 mg phenylephrine HCl, fed. ...Th …
Test treatments were 25 mg phenylephrine tannate (equivalent to 10 mg phenylephrine HCl) combined with 200 mg guaifenesin …