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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 1
1981 1
1985 1
1986 1
1987 1
1988 1
1992 1
1993 2
1994 1
1996 1
1997 2
1998 1
1999 2
2000 4
2001 2
2002 8
2003 4
2004 6
2005 10
2006 9
2007 7
2008 5
2009 14
2010 9
2011 6
2012 7
2013 7
2014 9
2015 12
2016 13
2017 11
2018 10
2019 9
2020 11
2021 18
2022 7
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198 results
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Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial.
Krebs EE, Gravely A, Nugent S, Jensen AC, DeRonne B, Goldsmith ES, Kroenke K, Bair MJ, Noorbaloochi S. Krebs EE, et al. JAMA. 2018 Mar 6;319(9):872-882. doi: 10.1001/jama.2018.0899. JAMA. 2018. PMID: 29509867 Free PMC article. Clinical Trial.
In the opioid group, the first step was immediate-release morphine, oxycodone, or hydrocodone/acetaminophen. For the nonopioid group, the first step was acetaminophen (paracetamol) or a nonsteroidal anti-inflammatory drug. ...
In the opioid group, the first step was immediate-release morphine, oxycodone, or hydrocodone/acetaminophen. For the nonopioid …
Effectiveness of Oxycodone Hydrochloride (Strong Opioid) vs Combination Acetaminophen and Codeine (Mild Opioid) for Subacute Pain After Fractures Managed Surgically: A Randomized Clinical Trial.
Jenkin DE, Naylor JM, Descallar J, Harris IA. Jenkin DE, et al. JAMA Netw Open. 2021 Nov 1;4(11):e2134988. doi: 10.1001/jamanetworkopen.2021.34988. JAMA Netw Open. 2021. PMID: 34787656 Free PMC article. Clinical Trial.
Data were analyzed from June through October 2018. INTERVENTIONS: Initiation at discharge of oxycodone hydrochloride 5 mg of 10 mg (ie, 1 or 2 tablets) or combination acetaminophen and codeine 500 mg and 8 mg or 1000 mg and 16 mg (ie, 1 or 2 tablets) 4 times daily f …
Data were analyzed from June through October 2018. INTERVENTIONS: Initiation at discharge of oxycodone hydrochloride 5 mg of 10 mg (i …
Assessment of Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery: A Randomized Clinical Trial.
Ayoub NF, Choby G, Turner JH, Abuzeid WM, Raviv JR, Thamboo A, Ma Y, Chandra RK, Chowdhury NI, Stokken JK, O'Brien EK, Shah S, Akbar N, Roozdar P, Nayak JV, Patel ZM, Hwang PH. Ayoub NF, et al. JAMA Otolaryngol Head Neck Surg. 2021 Sep 1;147(9):811-819. doi: 10.1001/jamaoto.2021.1839. JAMA Otolaryngol Head Neck Surg. 2021. PMID: 34351376 Free PMC article. Clinical Trial.
Thirty-two (63%) in the oxycodone rescue group had adequate pain management with acetaminophen only, while 19 (37%) consumed at least 1 oxycodone dose. In the ibuprofen rescue group, 18 (16%) required only acetaminophen, 28 (57%) used only acetamino
Thirty-two (63%) in the oxycodone rescue group had adequate pain management with acetaminophen only, while 19 (37%) consumed a …
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Ilyas AM, Miller AJ, Graham JG, Matzon JL. Ilyas AM, et al. Orthopedics. 2019 Mar 1;42(2):110-115. doi: 10.3928/01477447-20190221-02. Epub 2019 Feb 27. Orthopedics. 2019. PMID: 30810754 Clinical Trial.
The goal of this study was to evaluate 3 common oral analgesics-oxycodone (OXY), ibuprofen (IBU), and acetaminophen (ACE)-for pain management following carpal tunnel release (CTR) and trigger finger release (TFR) surgery. ...
The goal of this study was to evaluate 3 common oral analgesics-oxycodone (OXY), ibuprofen (IBU), and acetaminophen (ACE)-for …
Multi-Modal Analgesic Strategy for Trauma: A Pragmatic Randomized Clinical Trial.
Harvin JA, Albarado R, Truong VTT, Green C, Tyson JE, Pedroza C, Wade CE, Kao LS; MAST Study Group. Harvin JA, et al. J Am Coll Surg. 2021 Mar;232(3):241-251.e3. doi: 10.1016/j.jamcollsurg.2020.12.014. Epub 2021 Jan 21. J Am Coll Surg. 2021. PMID: 33486130 Free PMC article. Clinical Trial.
METHODS: This was an unblinded, pragmatic, randomized, comparative effectiveness trial of all adult trauma admissions except vulnerable patient populations and readmissions. The original MMPR (IV administration, followed by oral, acetaminophen, 48 hours of celecoxib and pr …
METHODS: This was an unblinded, pragmatic, randomized, comparative effectiveness trial of all adult trauma admissions except vulnerable pati …
Pharmacokinetics and bioavailability of oxycodone and acetaminophen following single-dose administration of MNK-795, a dual-layer biphasic IR/ER combination formulation, under fed and fasted conditions.
Devarakonda K, Morton T, Margulis R, Giuliani M, Barrett T. Devarakonda K, et al. Drug Des Devel Ther. 2014 Aug 19;8:1125-34. doi: 10.2147/DDDT.S64261. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25170252 Free PMC article. Clinical Trial.
BACKGROUND: XARTEMIS XR (formerly MNK-795) is a combination oxycodone (OC) and acetaminophen (APAP) analgesic with both immediate-release and extended-release (ER) components (ER OC/APAP). ...Both oxycodone and APAP were rapidly absorbed under fasted conditio …
BACKGROUND: XARTEMIS XR (formerly MNK-795) is a combination oxycodone (OC) and acetaminophen (APAP) analgesic with both immedi …
A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen.
Friedman BW, Irizarry E, Feliciano C, Izzo AJ, Borrayes L, Restivo A, Costa V, Bijur PE. Friedman BW, et al. Acad Emerg Med. 2021 Aug;28(8):859-865. doi: 10.1111/acem.14231. Epub 2021 Mar 12. Acad Emerg Med. 2021. PMID: 33576545 Free article. Clinical Trial.
A total of 159 (40%) patients reported inadequate relief after 1 h had elapsed. A total of 154 of these were randomized, 77 to oxycodone/acetaminophen and 77 to acetaminophen. Baseline characteristics were comparable. Among patients randomized to oxycodone
A total of 159 (40%) patients reported inadequate relief after 1 h had elapsed. A total of 154 of these were randomized, 77 to oxycodone
The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain.
Bebee B, Taylor DM, Bourke E, Pollack K, Foster L, Ching M, Wong A. Bebee B, et al. Med J Aust. 2021 May;214(8):370-375. doi: 10.5694/mja2.51014. Epub 2021 Apr 12. Med J Aust. 2021. PMID: 33846971 Clinical Trial.
The median length of stay was 9.0 hours (IQR, 7.4-12 hours) for the CBD group and 8.5 hours (IQR, 6.5-21 hours) for the placebo group. Oxycodone use during the four hours preceding and the four hours after receiving CBD or placebo was similar for the two groups, as were re …
The median length of stay was 9.0 hours (IQR, 7.4-12 hours) for the CBD group and 8.5 hours (IQR, 6.5-21 hours) for the placebo group. Ox
Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone.
Ilyas AM, Miller AJ, Graham JG, Matzon JL. Ilyas AM, et al. J Hand Surg Am. 2018 Oct;43(10):913-919. doi: 10.1016/j.jhsa.2018.08.011. J Hand Surg Am. 2018. PMID: 30286851 Clinical Trial.
The purpose of this study was to determine if there was a difference in pain levels or pill consumption when using nonopioids, ibuprofen (IBU) and acetaminophen (ACE), versus an opioid, oxycodone (OXY), after carpal tunnel release (CTR) performed exclusively under l …
The purpose of this study was to determine if there was a difference in pain levels or pill consumption when using nonopioids, ibuprofen (IB …
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
Friedman BW, Dym AA, Davitt M, Holden L, Solorzano C, Esses D, Bijur PE, Gallagher EJ. Friedman BW, et al. JAMA. 2015 Oct 20;314(15):1572-80. doi: 10.1001/jama.2015.13043. JAMA. 2015. PMID: 26501533 Clinical Trial.
At baseline, median RMDQ score in the placebo group was 20 (interquartile range [IQR],17-21), in the cyclobenzaprine group 19 (IQR,17-21), and in the oxycodone/acetaminophen group 20 (IQR,17-22). At 1-week follow-up, the mean RMDQ improvement was 9.8 in the placebo …
At baseline, median RMDQ score in the placebo group was 20 (interquartile range [IQR],17-21), in the cyclobenzaprine group 19 (IQR,17-21), a …
198 results