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2004 25
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2006 15
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2010 10
2011 15
2012 14
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599 results

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Page 1
Acetazolamide in Acute Decompensated Heart Failure with Volume Overload.
Mullens W, Dauw J, Martens P, Verbrugge FH, Nijst P, Meekers E, Tartaglia K, Chenot F, Moubayed S, Dierckx R, Blouard P, Troisfontaines P, Derthoo D, Smolders W, Bruckers L, Droogne W, Ter Maaten JM, Damman K, Lassus J, Mebazaa A, Filippatos G, Ruschitzka F, Dupont M; ADVOR Study Group. Mullens W, et al. N Engl J Med. 2022 Sep 29;387(13):1185-1195. doi: 10.1056/NEJMoa2203094. Epub 2022 Aug 27. N Engl J Med. 2022. PMID: 36027559 Clinical Trial.
Successful decongestion occurred in 108 of 256 patients (42.2%) in the acetazolamide group and in 79 of 259 (30.5%) in the placebo group (risk ratio, 1.46; 95% confidence interval [CI], 1.17 to 1.82; P<0.001). ...Acetazolamide treatment was associated with higher …
Successful decongestion occurred in 108 of 256 patients (42.2%) in the acetazolamide group and in 79 of 259 (30.5%) in the placebo gr …
Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial.
NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee; Wall M, McDermott MP, Kieburtz KD, Corbett JJ, Feldon SE, Friedman DI, Katz DM, Keltner JL, Schron EB, Kupersmith MJ. NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee, et al. JAMA. 2014 Apr 23-30;311(16):1641-51. doi: 10.1001/jama.2014.3312. JAMA. 2014. PMID: 24756514 Free PMC article. Clinical Trial.

Mean improvements in papilledema grade (acetazolamide: -1.31, from 2.76 to 1.45; placebo: -0.61, from 2.76 to 2.15; treatment effect, -0.70; 95% CI, -0.99 to -0.41; P < .001) and vision-related quality of life as measured by the National Eye Institute VFQ-25 (acetazo

Mean improvements in papilledema grade (acetazolamide: -1.31, from 2.76 to 1.45; placebo: -0.61, from 2.76 to 2.15; treatment effect, …
Acetazolamide therapy.
Millichap JG. Millichap JG. Neurology. 1991 May;41(5):764. doi: 10.1212/wnl.41.5.764. Neurology. 1991. PMID: 1902920 Clinical Trial. No abstract available.
Pre-treatment bicarbonate levels and decongestion by acetazolamide: the ADVOR trial.
Martens P, Verbrugge FH, Dauw J, Nijst P, Meekers E, Augusto SN, Ter Maaten JM, Heylen L, Damman K, Mebazaa A, Filippatos G, Ruschitzka F, Tang WHW, Dupont M, Mullens W. Martens P, et al. Eur Heart J. 2023 Jun 9;44(22):1995-2005. doi: 10.1093/eurheartj/ehad236. Eur Heart J. 2023. PMID: 37138385 Free article. Clinical Trial.
AIMS: Acetazolamide inhibits proximal tubular sodium and bicarbonate re-absorption and improved decongestive response in acute heart failure in the ADVOR trial. ...Randomization towards acetazolamide improved decongestive response over the entire range of baseline H …
AIMS: Acetazolamide inhibits proximal tubular sodium and bicarbonate re-absorption and improved decongestive response in acute heart …
Randomized clinical trial of acetazolamide administration and/or prone positioning in mitigating wound complications following untethering surgeries.
Shahjouei S, Hanaei S, Habibi Z, Hoseini M, Ansari S, Nejat F. Shahjouei S, et al. J Neurosurg Pediatr. 2016 Jun;17(6):659-66. doi: 10.3171/2015.8.PEDS15393. Epub 2016 Jan 29. J Neurosurg Pediatr. 2016. PMID: 26824595 Clinical Trial.
The purpose of this randomized clinical trial was to evaluate the effectiveness of prone positioning and acetazolamide administration on complication rates following spinal cord untethering surgeries. METHODS From October 2012 to February 2015, patients with a primary diag …
The purpose of this randomized clinical trial was to evaluate the effectiveness of prone positioning and acetazolamide administration …
[Acetazolamide in acute heart failure].
Jolti M, Darbellay Farhoumand P, Carballo D, Carballo S. Jolti M, et al. Rev Med Suisse. 2023 Oct 25;19(847):2002-2006. doi: 10.53738/REVMED.2023.19.847.2002. Rev Med Suisse. 2023. PMID: 37878100 Clinical Trial. French.
A recent multicentric randomised controlled trial studied the administration of acetazolamide in addition to standard care with loop diuretics in the acute setting. There was a significantly faster decongestion, based on a pragmatic clinical score, with very few side effec …
A recent multicentric randomised controlled trial studied the administration of acetazolamide in addition to standard care with loop …
Renal function and decongestion with acetazolamide in acute decompensated heart failure: the ADVOR trial.
Meekers E, Dauw J, Martens P, Dhont S, Verbrugge FH, Nijst P, Ter Maaten JM, Damman K, Mebazaa A, Filippatos G, Ruschitzka F, Tang WHW, Dupont M, Mullens W. Meekers E, et al. Eur Heart J. 2023 Oct 1;44(37):3672-3682. doi: 10.1093/eurheartj/ehad557. Eur Heart J. 2023. PMID: 37623428 Free article. Clinical Trial.
BACKGROUND AND AIMS: In the ADVOR trial, acetazolamide improved decongestion in acute decompensated heart failure (ADHF). Whether the beneficial effects of acetazolamide are consistent across the entire range of renal function remains unclear. ...Overall, natriuresi …
BACKGROUND AND AIMS: In the ADVOR trial, acetazolamide improved decongestion in acute decompensated heart failure (ADHF). Whether the …
Effects of acetazolamide on pulmonary artery pressure and prevention of high-altitude pulmonary edema after rapid active ascent to 4,559 m.
Berger MM, Sareban M, Schiefer LM, Swenson KE, Treff F, Schäfer L, Schmidt P, Schimke MM, Paar M, Niebauer J, Cogo A, Kriemler S, Schwery S, Pickerodt PA, Mayer B, Bärtsch P, Swenson ER. Berger MM, et al. J Appl Physiol (1985). 2022 Jun 1;132(6):1361-1369. doi: 10.1152/japplphysiol.00806.2021. Epub 2022 May 5. J Appl Physiol (1985). 2022. PMID: 35511718 Free article. Clinical Trial.
Acetazolamide prevents acute mountain sickness (AMS) by inhibition of carbonic anhydrase. ...Our data do not support recommending acetazolamide for HAPE prevention....
Acetazolamide prevents acute mountain sickness (AMS) by inhibition of carbonic anhydrase. ...Our data do not support recommending
Diuresis Efficacy in Ambulatory Congested Heart Failure Patients: Intrapatient Comparison of 3 Diuretic Regimens (DEA-HF).
Abbo AR, Gruber A, Volis I, Aronson D, Girerd N, Lund Kristensen S, Zukermann R, Alberkant N, Sitnitsky E, Kruger A, Khasis P, Bravo E, Elad B, Helmer Levin L, Caspi O. Abbo AR, et al. JACC Heart Fail. 2024 Aug;12(8):1396-1405. doi: 10.1016/j.jchf.2024.04.014. Epub 2024 May 11. JACC Heart Fail. 2024. PMID: 38739124 Free article. Clinical Trial.
Administration of furosemide plus metolazone resulted in the highest weight of sodium excreted, 4,691 mg (95% CI: 4,153-5,229 mg) compared with furosemide alone, 3,835 mg (95% CI: 3,279-4,392 mg; P = 0.015) and to furosemide plus acetazolamide 3,584 mg (95% CI: 3,020-4,148 …
Administration of furosemide plus metolazone resulted in the highest weight of sodium excreted, 4,691 mg (95% CI: 4,153-5,229 mg) compared w …
Combination pharmacological therapy targeting multiple mechanisms of sleep apnoea: a randomised controlled cross-over trial.
Sands SA, Collet J, Gell LK, Calianese N, Hess LB, Vena D, Azarbarzin A, Bertisch SM, Landry S, Thomson L, Joosten SA, Hamilton GS, Edwards BA. Sands SA, et al. Thorax. 2024 Feb 15;79(3):259-268. doi: 10.1136/thorax-2023-220184. Thorax. 2024. PMID: 38286618 Clinical Trial.
Given the different pathophysiological mechanisms targeted by each intervention, we tested whether AtoOxy-plus-acetazolamide would be more efficacious than AtoOxy alone. METHODS: In a multicentre randomised crossover trial, 19 patients with moderate-to-severe OSA received …
Given the different pathophysiological mechanisms targeted by each intervention, we tested whether AtoOxy-plus-acetazolamide would be …
599 results