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Page 1
Effect of acetohydroxamic acid on dissolution of canine struvite uroliths.
Krawiec DR, Osborne CA, Leininger JR, Griffith DP. Krawiec DR, et al. Am J Vet Res. 1984 Jul;45(7):1266-75. Am J Vet Res. 1984. PMID: 24049882 Clinical Trial.
Long-term administration of acetohydroxamic acid to dogs with experimentally induced urease-positive staphylococcal urinary tract infections and struvite urolithiasis resulted in dose-dependent inhibition of urolith growth or urolith dissolution. ...Lesions of the u …
Long-term administration of acetohydroxamic acid to dogs with experimentally induced urease-positive staphylococcal urinary tr …
Effectiveness of Treatment Modalities on Kidney Stone Recurrence.
Zisman AL. Zisman AL. Clin J Am Soc Nephrol. 2017 Oct 6;12(10):1699-1708. doi: 10.2215/CJN.11201016. Epub 2017 Aug 22. Clin J Am Soc Nephrol. 2017. PMID: 28830863 Free PMC article. Review.
Management of struvite stone disease is largely surgical, but acetohydroxamic acid is a proven second line therapy. Cystinuria requires lifestyle modifications and may call for thiol-binding agents. ...
Management of struvite stone disease is largely surgical, but acetohydroxamic acid is a proven second line therapy. Cystinuria …
New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate.
Lake KD, Brown DC. Lake KD, et al. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. doi: 10.1177/106002808501900705. Drug Intell Clin Pharm. 1985. PMID: 3896714 Review.
Cellulose sodium phosphate (Calcibind) is a nonabsorbable ion-exchange resin with a limited indication for the treatment of calcium stones associated with absorptive hypercalciuria Type I. Acetohydroxamic acid (Lithostat) is an urease-inhibitor that is indicated as …
Cellulose sodium phosphate (Calcibind) is a nonabsorbable ion-exchange resin with a limited indication for the treatment of calcium stones a …
A randomized trial of acetohydroxamic acid for the treatment and prevention of infection-induced urinary stones in spinal cord injury patients.
Griffith DP, Khonsari F, Skurnick JH, James KE. Griffith DP, et al. J Urol. 1988 Aug;140(2):318-24. doi: 10.1016/s0022-5347(17)41592-8. J Urol. 1988. PMID: 3294442 Clinical Trial.
Acetohydroxamic acid is known to inhibit bacterial urease activity, thus, reducing urinary ammonia levels. ...Of the acetohydroxamic acid and placebo patients 62 and 29 per cent, respectively, reported drug side effects but all were reversible a …
Acetohydroxamic acid is known to inhibit bacterial urease activity, thus, reducing urinary ammonia levels. ...Of the acetoh …
Formation of struvite urinary stones and approaches towards the inhibition-A review.
Das P, Gupta G, Velu V, Awasthi R, Dua K, Malipeddi H. Das P, et al. Biomed Pharmacother. 2017 Dec;96:361-370. doi: 10.1016/j.biopha.2017.10.015. Epub 2017 Nov 24. Biomed Pharmacother. 2017. PMID: 29028588 Review.
Herbal extracts of curcumin, Boerhaavia diffusa Linn, Rotula aquatica and many other plants, as well as some chemicals like pyrophosphate, acetohydroxamic acid, disodium EDTA and trisodium citrate, were reported to successfully inhibit struvite formation. ...Most of …
Herbal extracts of curcumin, Boerhaavia diffusa Linn, Rotula aquatica and many other plants, as well as some chemicals like pyrophosphate, …
Acetohydroxamic acid. Potential use in urinary infection caused by urea-splitting bacteria.
Griffith DP, Musher DM. Griffith DP, et al. Urology. 1975 Mar;05(3):299-302. doi: 10.1016/0090-4295(75)90142-9. Urology. 1975. PMID: 1118989
Of the cogeners studied, to dat, AHA (acetohydroxamic acid) appears to have the most pharmacologic potential. AHA is rapidly and completely absorbed from the gastrointestinal tract and is concentrated and excreted in the urine. ...
Of the cogeners studied, to dat, AHA (acetohydroxamic acid) appears to have the most pharmacologic potential. AHA is rapidly a …
Effect of acetohydroxamic acid on prevention of canine struvite uroliths.
Krawiec DR, Osborne CA, Leininger JR, Griffith DP. Krawiec DR, et al. Am J Vet Res. 1984 Jul;45(7):1276-82. Am J Vet Res. 1984. PMID: 24049883 Clinical Trial.
Long-term administration of acetohydroxamic acid (AHA) to dogs with experimentally induced urease-positive staphylococcal urinary tract infections, and bladder zinc disk foreign bodies inhibited urolith growth in 2 dogs and prevented urolith growth in 4 dogs. ...
Long-term administration of acetohydroxamic acid (AHA) to dogs with experimentally induced urease-positive staphylococcal urin …
Acetohydroxamic acid: clinical studies of a urease inhibitor in patients with staghorn renal calculi.
Griffith DP, Gibson JR, Clinton CW, Musher DM. Griffith DP, et al. J Urol. 1978 Jan;119(1):9-15. doi: 10.1016/s0022-5347(17)57366-8. J Urol. 1978. PMID: 23442
These factors contribute to the formation of urinary stones and to the virulence of bacteria. Acetohydroxamic acid, a potent inhibitor of urease, has been administered to 23 patients with staghorn renal calculi and urea-splitting urinary infection. Urinary ammonia a …
These factors contribute to the formation of urinary stones and to the virulence of bacteria. Acetohydroxamic acid, a potent i …
A randomized double-blind study of acetohydroxamic acid in struvite nephrolithiasis.
Williams JJ, Rodman JS, Peterson CM. Williams JJ, et al. N Engl J Med. 1984 Sep 20;311(12):760-4. doi: 10.1056/NEJM198409203111203. N Engl J Med. 1984. PMID: 6472365 Clinical Trial.
We studied the effects of the bacterial urease inhibitor acetohydroxamic acid on the growth of struvite stones in the urinary tract. ...Seven patients given placebo reached a pre-determined end point: a 100 per cent increase in the two-dimensional surface are …
We studied the effects of the bacterial urease inhibitor acetohydroxamic acid on the growth of struvite stones in the u …
Novel Lipophilic Hydroxamates Based on Spirocarbocyclic Hydantoin Scaffolds with Potent Antiviral and Trypanocidal Activity.
Pardali V, Giannakopoulou E, Mpekoulis G, Tsopela V, Panos G, Taylor MC, Kelly JM, Vassilaki N, Zoidis G. Pardali V, et al. Pharmaceuticals (Basel). 2023 Jul 24;16(7):1046. doi: 10.3390/ph16071046. Pharmaceuticals (Basel). 2023. PMID: 37513957 Free PMC article.
The tropical parasites Trypanosoma brucei and Trypanosoma cruzi cause enormous socioeconomic burdens in Sub-Saharan Africa and Latin America. Anti-HCV chemotherapy has severe adverse effects and is expensive, whereas dengue has no clinically authorized treatment. .. …
The tropical parasites Trypanosoma brucei and Trypanosoma cruzi cause enormous socioeconomic burdens in Sub-Saharan Africa and Latin America …
47 results