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504 results

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Page 1
Urease stones.
Griffith DP. Griffith DP. Urol Res. 1979 Sep;7(3):215-21. doi: 10.1007/BF00257208. Urol Res. 1979. PMID: 388798 Review.
Recurrent stone formation and progressive pyelonephritis occur in those who are not cured. Adjunctive medical treatment with acetohydroxamic acid or hydroxyurea lessens the risk of calculogenesis and decreases growth of residual stones in patients who are not cured …
Recurrent stone formation and progressive pyelonephritis occur in those who are not cured. Adjunctive medical treatment with acetohydroxa …
The effectiveness of citrates and pyridoxine in the treatment of kidney stones.
Ene MA, Geavlete PA, Simeanu CE, Bulai CA, Ene CV, Geavlete BF. Ene MA, et al. J Med Life. 2023 Jun;16(6):856-861. doi: 10.25122/jml-2023-0234. J Med Life. 2023. PMID: 37675156 Free PMC article. Review.
In cases of struvite stones, which often necessitate a surgical approach, acetohydroxamic acid emerges as a valuable second-line treatment option. Thiol-binding agents may be needed for cystinuria, as well as lifestyle modifications. ...
In cases of struvite stones, which often necessitate a surgical approach, acetohydroxamic acid emerges as a valuable second-li …
Gamma Radiation-Induced Degradation of Acetohydroxamic Acid (AHA) in Aqueous Nitrate and Nitric Acid Solutions Evaluated by Multiscale Modelling.
Conrad JK, Mezyk SP, Isherwood LH, Baidak A, Pilgrim CD, Whittaker D, Orr RM, Pimblott SM, Horne GP. Conrad JK, et al. Chemphyschem. 2023 Mar 1;24(5):e202200749. doi: 10.1002/cphc.202200749. Epub 2022 Dec 5. Chemphyschem. 2023. PMID: 36470592
Acetohydroxamic acid (AHA) has been proposed for inclusion in advanced, single-cycle, used nuclear fuel reprocessing solvent systems for the reduction and complexation of plutonium and neptunium ions. ...
Acetohydroxamic acid (AHA) has been proposed for inclusion in advanced, single-cycle, used nuclear fuel reprocessing solvent s …
Effectiveness of Treatment Modalities on Kidney Stone Recurrence.
Zisman AL. Zisman AL. Clin J Am Soc Nephrol. 2017 Oct 6;12(10):1699-1708. doi: 10.2215/CJN.11201016. Epub 2017 Aug 22. Clin J Am Soc Nephrol. 2017. PMID: 28830863 Free PMC article. Review.
Management of struvite stone disease is largely surgical, but acetohydroxamic acid is a proven second line therapy. Cystinuria requires lifestyle modifications and may call for thiol-binding agents. ...
Management of struvite stone disease is largely surgical, but acetohydroxamic acid is a proven second line therapy. Cystinuria …
A randomized trial of acetohydroxamic acid for the treatment and prevention of infection-induced urinary stones in spinal cord injury patients.
Griffith DP, Khonsari F, Skurnick JH, James KE. Griffith DP, et al. J Urol. 1988 Aug;140(2):318-24. doi: 10.1016/s0022-5347(17)41592-8. J Urol. 1988. PMID: 3294442 Clinical Trial.
Acetohydroxamic acid is known to inhibit bacterial urease activity, thus, reducing urinary ammonia levels. ...The study data support the usefulness of acetohydroxamic acid in reducing urinary ammonia. At every followup visit the acetohydroxamic …
Acetohydroxamic acid is known to inhibit bacterial urease activity, thus, reducing urinary ammonia levels. ...The study data s …
Effect of acetohydroxamic acid on dissolution of canine struvite uroliths.
Krawiec DR, Osborne CA, Leininger JR, Griffith DP. Krawiec DR, et al. Am J Vet Res. 1984 Jul;45(7):1266-75. Am J Vet Res. 1984. PMID: 24049882 Clinical Trial.
Long-term administration of acetohydroxamic acid to dogs with experimentally induced urease-positive staphylococcal urinary tract infections and struvite urolithiasis resulted in dose-dependent inhibition of urolith growth or urolith dissolution. ...Lesions of the u …
Long-term administration of acetohydroxamic acid to dogs with experimentally induced urease-positive staphylococcal urinary tr …
Recent Efforts in the Discovery of Urease Inhibitor Identifications.
Song WQ, Liu ML, Li SY, Xiao ZP. Song WQ, et al. Curr Top Med Chem. 2022;22(2):95-107. doi: 10.2174/1568026621666211129095441. Curr Top Med Chem. 2022. PMID: 34844543 Review.
In the past century, hundreds of medicinal chemists focused their efforts on explorations of urease inhibitors. Despite the FDA's approval of acetohydroxamic acid as a urease inhibitor for the treatment of struvite nephrolithiasis and the widespread use of N-(n-buty …
In the past century, hundreds of medicinal chemists focused their efforts on explorations of urease inhibitors. Despite the FDA's approval o …
One-electron oxidation of acetohydroxamic acid: the intermediacy of nitroxyl and peroxynitrite.
Samuni A, Goldstein S. Samuni A, et al. J Phys Chem A. 2011 Apr 14;115(14):3022-8. doi: 10.1021/jp201796q. Epub 2011 Mar 22. J Phys Chem A. 2011. PMID: 21425838
In the present study, one-electron oxidation of acetohydroxamic acid (aceto-HX) by ()OH, ()N(3), ()NO(2), CO(3)(-), and O(2)(-) radicals was investigated using pulse radiolysis. ...
In the present study, one-electron oxidation of acetohydroxamic acid (aceto-HX) by ()OH, ()N(3), ()NO(2), CO(3)(-), and O(2)(- …
Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro.
Liu YH, Lu YL, Liu DZ, Hou WC. Liu YH, et al. Drug Des Devel Ther. 2017 Jul 13;11:2139-2147. doi: 10.2147/DDDT.S141740. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 28761331 Free PMC article.
Advanced glycation endproducts (AGEs) can promote intracellular reactive oxygen species production, and the levels of AGEs are highly correlated with cardiovascular disease and diabetes complications. Acetohydroxamic acid (acetH) is a bacterial urease inhibitor drug …
Advanced glycation endproducts (AGEs) can promote intracellular reactive oxygen species production, and the levels of AGEs are highly correl …
New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate.
Lake KD, Brown DC. Lake KD, et al. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. doi: 10.1177/106002808501900705. Drug Intell Clin Pharm. 1985. PMID: 3896714 Review.
Cellulose sodium phosphate (Calcibind) is a nonabsorbable ion-exchange resin with a limited indication for the treatment of calcium stones associated with absorptive hypercalciuria Type I. Acetohydroxamic acid (Lithostat) is an urease-inhibitor that is indicated as …
Cellulose sodium phosphate (Calcibind) is a nonabsorbable ion-exchange resin with a limited indication for the treatment of calcium stones a …
504 results