Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 5
1981 18
1982 38
1983 56
1984 42
1985 42
1986 38
1987 29
1988 56
1989 31
1990 23
1991 47
1992 39
1993 45
1994 56
1995 69
1996 71
1997 59
1998 59
1999 54
2000 49
2001 47
2002 46
2003 48
2004 38
2005 35
2006 34
2007 36
2008 46
2009 57
2010 47
2011 42
2012 43
2013 27
2014 17
2015 29
2016 27
2017 21
2018 21
2019 20
2020 17
2021 18
2022 7
2023 12
2024 18
2025 17
2026 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

1,636 results

Results by year

Filters applied: . Clear all
Page 1
Acyclovir: mechanism of action, pharmacokinetics, safety and clinical applications.
Gnann JW Jr, Barton NH, Whitley RJ. Gnann JW Jr, et al. Pharmacotherapy. 1983 Sep-Oct;3(5):275-83. doi: 10.1002/j.1875-9114.1983.tb03274.x. Pharmacotherapy. 1983. PMID: 6359082 Review.
Acyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. ...An investigational oral preparation may prove to be effective therapy for both initial and recurrent genital herpes. Acyclovir therapy does not eliminate latent vir …
Acyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. ...An investigational oral prepara …
Herpetic Eye Disease Study. A controlled trial of oral acyclovir for herpes simplex stromal keratitis.
Barron BA, Gee L, Hauck WW, Kurinij N, Dawson CR, Jones DB, Wilhelmus KR, Kaufman HE, Sugar J, Hyndiuk RA, et al. Barron BA, et al. Ophthalmology. 1994 Dec;101(12):1871-82. doi: 10.1016/s0161-6420(13)31155-5. Ophthalmology. 1994. PMID: 7997323 Clinical Trial.
By 16 weeks, 38 patients (75%) in the acyclovir group and 39 patients (74%) in the placebo group had failed treatment. Also by that time, the keratitis had resolved with trial medications, and there was no subsequent worsening in nine patients (18%) in the acyclovir …
By 16 weeks, 38 patients (75%) in the acyclovir group and 39 patients (74%) in the placebo group had failed treatment. Also by that t …
Antiviral drugs 1983.
Douglas RG Jr. Douglas RG Jr. Med Clin North Am. 1983 Sep;67(5):1163-72. doi: 10.1016/s0025-7125(16)31172-5. Med Clin North Am. 1983. PMID: 6194388 Review.
Trifluridine, idoxuridine, and vidarabine are effective topically in herpes simplex virus keratoconjunctivitis infection. Vidarabine (and presumably acyclovir) is effective in herpes simplex virus encephalitis and in herpes zoster infections in the immunocompromised host. …
Trifluridine, idoxuridine, and vidarabine are effective topically in herpes simplex virus keratoconjunctivitis infection. Vidarabine (and pr …
Acyclovir efficacy for bell's palsy treatment.
Günebakan Ç, Kuzu S, Bozkurt E. Günebakan Ç, et al. Am J Otolaryngol. 2025 Sep-Oct;46(5):104637. doi: 10.1016/j.amjoto.2025.104637. Epub 2025 Apr 28. Am J Otolaryngol. 2025. PMID: 40580762 Free article. Clinical Trial.
PURPOSE: This study aims to analyze the results regarding prednisolone alone, and the combined use of acyclovir with prednisolone in the treatment modality of Bell's palsy. METHODS: In this prospective, randomized clinical study, which was held in a single tertiary hospita …
PURPOSE: This study aims to analyze the results regarding prednisolone alone, and the combined use of acyclovir with prednisolone in …
Acyclovir in shingles.
Bean B, Aeppli D, Balfour HH Jr. Bean B, et al. J Antimicrob Chemother. 1983 Sep;12 Suppl B:123-7. doi: 10.1093/jac/12.suppl_b.123. J Antimicrob Chemother. 1983. PMID: 6355047 Review.
Acyclovir given intravenously in either low dose (5 mg/kg every 8 h) or high dose (500 mg/m2 every 8 h) significantly reduced pain and accelerated skin healing in acute herpes zoster occurring in otherwise healthy adults. ...No adverse effects were associated with the lowe …
Acyclovir given intravenously in either low dose (5 mg/kg every 8 h) or high dose (500 mg/m2 every 8 h) significantly reduced pain an …
Management of Epstein-Barr virus infections.
Andersson J, Ernberg I. Andersson J, et al. Am J Med. 1988 Aug 29;85(2A):107-15. Am J Med. 1988. PMID: 2841854 Review.
Acyclovir treatment is effective in the EBV-genome positive hairy leukoplakia in human immunodeficiency virus-seropositive patients. ...Prophylactic use of immunoglobulin or acyclovir has been suggested in susceptible children....
Acyclovir treatment is effective in the EBV-genome positive hairy leukoplakia in human immunodeficiency virus-seropositive patients. …
Randomized clinical trial of famciclovir or acyclovir for the treatment of herpes zoster in adults.
Pott Junior H, de Oliveira MFB, Gambero S, Amazonas RB. Pott Junior H, et al. Int J Infect Dis. 2018 Jul;72:11-15. doi: 10.1016/j.ijid.2018.04.4324. Epub 2018 May 7. Int J Infect Dis. 2018. PMID: 29746903 Free article. Clinical Trial.
RESULTS: One hundred and seventy-four patients were enrolled and randomized; 151 of these patients completed treatment (n=75 famciclovir, n=76 acyclovir). A similar proportion of patients who received acyclovir (94.74%) and famciclovir (94.67%) achieved complete cur …
RESULTS: One hundred and seventy-four patients were enrolled and randomized; 151 of these patients completed treatment (n=75 famciclovir, n= …
Therapeutic effects of acyclovir and acyclovir-clobetasol nanofibers vs. cream formulation for recurrent herpes labialis.
Mirzaei S, Nejad ZG, Khozaimeh F, Mohammadi S, Loqmani A. Mirzaei S, et al. BMC Oral Health. 2024 Nov 6;24(1):1348. doi: 10.1186/s12903-024-04948-6. BMC Oral Health. 2024. PMID: 39506756 Free PMC article. Clinical Trial.
MATERIALS AND METHODS: Eighty patients with labial herpes lesions were divided into four groups, each receiving one of the following treatments: acyclovir-clobetasol nano patch, acyclovir-clobetasol cream, acyclovir nano patch, or acyclovir cream. ...T …
MATERIALS AND METHODS: Eighty patients with labial herpes lesions were divided into four groups, each receiving one of the following treatme …
Acyclovir, herpes, and pregnancy.
Brocklehurst P, Carney O, Helson K, Kinghorn G, Mercey D, Mindel A. Brocklehurst P, et al. Lancet. 1990 Dec 22-29;336(8730):1594-5. doi: 10.1016/0140-6736(90)93384-2. Lancet. 1990. PMID: 1979417 Clinical Trial. No abstract available.
Double-blind clinical trial of acyclovir and adenine arabinoside in herpetic corneal ulceration.
Young B, Patterson A, Ravenscroft T. Young B, et al. Am J Med. 1982 Jul 20;73(1A):311-2. doi: 10.1016/0002-9343(82)90113-9. Am J Med. 1982. PMID: 7048918 Clinical Trial.
The results of a double-blind clinical trials of acyclovir and adenosine arabinoside (ara-A) in 93 patients with herpetic keratitis demonstrated a significantly faster healing rate for acyclovir (p less than 0.01). Ulcers in 45 (94 percent) of acyclovir-treat …
The results of a double-blind clinical trials of acyclovir and adenosine arabinoside (ara-A) in 93 patients with herpetic keratitis d …
1,636 results