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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 5
1981 18
1982 38
1983 56
1984 42
1985 42
1986 38
1987 29
1988 56
1989 31
1990 23
1991 47
1992 39
1993 45
1994 56
1995 69
1996 71
1997 59
1998 59
1999 54
2000 49
2001 47
2002 46
2003 48
2004 38
2005 35
2006 34
2007 36
2008 46
2009 57
2010 47
2011 42
2012 43
2013 27
2014 17
2015 30
2016 27
2017 22
2018 20
2019 21
2020 17
2021 10
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1,579 results
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Page 1
Acyclovir: mechanism of action, pharmacokinetics, safety and clinical applications.
Gnann JW Jr, Barton NH, Whitley RJ. Gnann JW Jr, et al. Pharmacotherapy. 1983 Sep-Oct;3(5):275-83. doi: 10.1002/j.1875-9114.1983.tb03274.x. Pharmacotherapy. 1983. PMID: 6359082 Review.
Acyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. ...An investigational oral preparation may prove to be effective therapy for both initial and recurrent genital herpes. Acyclovir therapy does not eliminate latent vir
Acyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. ...An investigational oral prepara
Acyclovir. A review of its pharmacodynamic properties and therapeutic efficacy.
Richards DM, Carmine AA, Brogden RN, Heel RC, Speight TM, Avery GS. Richards DM, et al. Drugs. 1983 Nov;26(5):378-438. doi: 10.2165/00003495-198326050-00002. Drugs. 1983. PMID: 6315332 Review.
Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine. ...Acyclovir ointment demonstrated little benefit in recurrent genital herpes but topical acyclovir cream decreased the cours
Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine.
Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults.
Beutner KR, Friedman DJ, Forszpaniak C, Andersen PL, Wood MJ. Beutner KR, et al. Antimicrob Agents Chemother. 1995 Jul;39(7):1546-53. doi: 10.1128/AAC.39.7.1546. Antimicrob Agents Chemother. 1995. PMID: 7492102 Free PMC article. Clinical Trial.
Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications. The limited oral bioavailability of acyclovir necessitates frequent dosing. Valaciclovir, the l-valyl ester of acyclovir, is rapidly and almost complet
Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications. The limited oral bioavail
Prospective, Controlled Study of Acyclovir Pharmacokinetics in Obese Patients.
Turner RB, Cumpston A, Sweet M, Briggs F, Slain D, Wen S, Craig M, Hamadani M, Petros W. Turner RB, et al. Antimicrob Agents Chemother. 2016 Jan 11;60(3):1830-3. doi: 10.1128/AAC.02010-15. Antimicrob Agents Chemother. 2016. PMID: 26824940 Free PMC article. Clinical Trial.
The current recommendations for intravenous (i.v.) acyclovir dosing in obese patients suggest using ideal body weight (IBW) rather than total body weight (TBW). ...Enrollment was conducted by 1:1 matching of obese patients (>190% of IBW) to normal-weight patients (80 to …
The current recommendations for intravenous (i.v.) acyclovir dosing in obese patients suggest using ideal body weight (IBW) rather th …
Herpetic Eye Disease Study. A controlled trial of oral acyclovir for herpes simplex stromal keratitis.
Barron BA, Gee L, Hauck WW, Kurinij N, Dawson CR, Jones DB, Wilhelmus KR, Kaufman HE, Sugar J, Hyndiuk RA, et al. Barron BA, et al. Ophthalmology. 1994 Dec;101(12):1871-82. doi: 10.1016/s0161-6420(13)31155-5. Ophthalmology. 1994. PMID: 7997323 Clinical Trial.
By 16 weeks, 38 patients (75%) in the acyclovir group and 39 patients (74%) in the placebo group had failed treatment. ...Visual acuity improved over 6 months in more patients in the acyclovir group than in the placebo group....
By 16 weeks, 38 patients (75%) in the acyclovir group and 39 patients (74%) in the placebo group had failed treatment. ...Visual acui …
Photodynamic therapy and Acyclovir in the treatment of recurrent herpes labialis: A controlled randomized clinical trial.
Ramalho KM, Cunha SR, Gonçalves F, Escudeiro GS, Steiner-Oliveira C, Horliana ACRT, Eduardo CP. Ramalho KM, et al. Photodiagnosis Photodyn Ther. 2021 Mar;33:102093. doi: 10.1016/j.pdpdt.2020.102093. Epub 2020 Nov 16. Photodiagnosis Photodyn Ther. 2021. PMID: 33212267 Clinical Trial.
This study aimed to compare photodynamic therapy (PDT), Topical Acyclovir (AC), and the association of both in the healing process and self-reported symptomologies of HSV-1 recurrences. ...
This study aimed to compare photodynamic therapy (PDT), Topical Acyclovir (AC), and the association of both in the healing process an …
Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial.
Semprini A, Singer J, Braithwaite I, Shortt N, Thayabaran D, McConnell M, Weatherall M, Beasley R. Semprini A, et al. BMJ Open. 2019 May 14;9(5):e026201. doi: 10.1136/bmjopen-2018-026201. BMJ Open. 2019. PMID: 31092654 Free PMC article. Clinical Trial.
OBJECTIVE: To compare New Zealand medical grade kanuka honey with topical aciclovir for the treatment of herpes simplex labialis. DESIGN: Prospective parallel randomised controlled open-label superiority trial. ...CONCLUSION: There was no evidence of a difference in effica …
OBJECTIVE: To compare New Zealand medical grade kanuka honey with topical aciclovir for the treatment of herpes simplex labialis. DES …
Phase I clinical trial of valacyclovir and standard of care cyclophosphamide in children with endemic Burkitt lymphoma in Malawi.
Olson D, Gulley ML, Tang W, Wokocha C, Mechanic O, Hosseinipour M, Gold SH, Nguluwe N, Mwansambo C, Shores C. Olson D, et al. Clin Lymphoma Myeloma Leuk. 2013 Apr;13(2):112-8. doi: 10.1016/j.clml.2012.11.003. Epub 2012 Dec 20. Clin Lymphoma Myeloma Leuk. 2013. PMID: 23260601 Free PMC article. Clinical Trial.
Phase II efficacy trials should now be undertaken. BACKGROUND: Nucleoside analogues, including acyclovir, ganciclovir, and their precursors, have shown some efficacy against several Epstein-Barr virus (EBV)-associated diseases, including active EBV infection and posttransp …
Phase II efficacy trials should now be undertaken. BACKGROUND: Nucleoside analogues, including acyclovir, ganciclovir, and their prec …
Current status and prospects for oral acyclovir treatment of first episode and recurrent genital herpes simplex virus.
Bryson YJ. Bryson YJ. J Antimicrob Chemother. 1983 Sep;12 Suppl B:61-5. doi: 10.1093/jac/12.suppl_b.61. J Antimicrob Chemother. 1983. PMID: 6355052 Review.
Herpes simplex genitalis is an increasingly common primary or recurrent HSV infection. Acyclovir (ACV) has been found to diminish virus shedding and clinical symptoms in patients with first episode genital HSV when given topically or intravenously. ...These effects were mo …
Herpes simplex genitalis is an increasingly common primary or recurrent HSV infection. Acyclovir (ACV) has been found to diminish vir …
1,579 results