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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 5
1981 18
1982 38
1983 56
1984 42
1985 42
1986 38
1987 29
1988 56
1989 31
1990 23
1991 47
1992 39
1993 45
1994 56
1995 69
1996 71
1997 59
1998 59
1999 54
2000 49
2001 47
2002 46
2003 48
2004 38
2005 35
2006 34
2007 36
2008 46
2009 57
2010 47
2011 42
2012 43
2013 27
2014 17
2015 30
2016 27
2017 22
2018 20
2019 20
2020 19
2021 18
2022 8
2023 12
2024 12

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1,615 results

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Page 1
Acyclovir: mechanism of action, pharmacokinetics, safety and clinical applications.
Gnann JW Jr, Barton NH, Whitley RJ. Gnann JW Jr, et al. Pharmacotherapy. 1983 Sep-Oct;3(5):275-83. doi: 10.1002/j.1875-9114.1983.tb03274.x. Pharmacotherapy. 1983. PMID: 6359082 Review.
Acyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. ...An investigational oral preparation may prove to be effective therapy for both initial and recurrent genital herpes. Acyclovir therapy does not eliminate latent vir
Acyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. ...An investigational oral prepara
Photodynamic therapy and Acyclovir in the treatment of recurrent herpes labialis: A controlled randomized clinical trial.
Ramalho KM, Cunha SR, Gonçalves F, Escudeiro GS, Steiner-Oliveira C, Horliana ACRT, Eduardo CP. Ramalho KM, et al. Photodiagnosis Photodyn Ther. 2021 Mar;33:102093. doi: 10.1016/j.pdpdt.2020.102093. Epub 2020 Nov 16. Photodiagnosis Photodyn Ther. 2021. PMID: 33212267 Clinical Trial.
This study aimed to compare photodynamic therapy (PDT), Topical Acyclovir (AC), and the association of both in the healing process and self-reported symptomologies of HSV-1 recurrences. ...
This study aimed to compare photodynamic therapy (PDT), Topical Acyclovir (AC), and the association of both in the healing process an …
A novel drug delivery system using acyclovir nanofiber patch for topical treatment of recurrent herpes labialis: A randomized clinical trial.
Golestannejad Z, Khozeimeh F, Mehrasa M, Mirzaeei S, Sarfaraz D. Golestannejad Z, et al. Clin Exp Dent Res. 2022 Feb;8(1):184-190. doi: 10.1002/cre2.512. Epub 2021 Dec 5. Clin Exp Dent Res. 2022. PMID: 34865318 Free PMC article. Clinical Trial.
The aim of this study was to compare the efficacy of acyclovir nanofiber patch with acyclovir cream. MATERIAL AND METHODS: In this double-blind three-armed randomized clinical trial, a total of 60 patients with recurrent labial herpes, were randomly divided into thr …
The aim of this study was to compare the efficacy of acyclovir nanofiber patch with acyclovir cream. MATERIAL AND METHODS: In …
Acyclovir in shingles.
Bean B, Aeppli D, Balfour HH Jr. Bean B, et al. J Antimicrob Chemother. 1983 Sep;12 Suppl B:123-7. doi: 10.1093/jac/12.suppl_b.123. J Antimicrob Chemother. 1983. PMID: 6355047 Review.
Acyclovir given intravenously in either low dose (5 mg/kg every 8 h) or high dose (500 mg/m2 every 8 h) significantly reduced pain and accelerated skin healing in acute herpes zoster occurring in otherwise healthy adults. ...No adverse effects were associated with the lowe
Acyclovir given intravenously in either low dose (5 mg/kg every 8 h) or high dose (500 mg/m2 every 8 h) significantly reduced pain an
Evaluation of oral acyclovir therapy.
Fletcher C, Bean B. Fletcher C, et al. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):518-24. doi: 10.1177/106002808501900703. Drug Intell Clin Pharm. 1985. PMID: 2992899 Review.
Oral acyclovir has an average plasma half-life of three hours and is eliminated primarily by renal mechanisms. ...Oral acyclovir represents a major therapeutic advance in the treatment of herpesvirus infections....
Oral acyclovir has an average plasma half-life of three hours and is eliminated primarily by renal mechanisms. ...Oral acyclovir
Herpes labialis in skiers: randomized clinical trial of acyclovir cream versus placebo.
Raborn GW, Martel AY, Grace MG, McGaw WT. Raborn GW, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Dec;84(6):641-5. doi: 10.1016/s1079-2104(97)90366-8. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997. PMID: 9431533 Clinical Trial.
CONCLUSION: The acyclovir group was significantly better than the placebo group during the follow-up period. The safety record of the drug was satisfactory; there was no difference between acyclovir and the placebo in side effects or pain. Topically applied 5% ac
CONCLUSION: The acyclovir group was significantly better than the placebo group during the follow-up period. The safety record of the …
Current status and prospects for oral acyclovir treatment of first episode and recurrent genital herpes simplex virus.
Bryson YJ. Bryson YJ. J Antimicrob Chemother. 1983 Sep;12 Suppl B:61-5. doi: 10.1093/jac/12.suppl_b.61. J Antimicrob Chemother. 1983. PMID: 6355052 Review.
Herpes simplex genitalis is an increasingly common primary or recurrent HSV infection. Acyclovir (ACV) has been found to diminish virus shedding and clinical symptoms in patients with first episode genital HSV when given topically or intravenously. ...These effects were mo …
Herpes simplex genitalis is an increasingly common primary or recurrent HSV infection. Acyclovir (ACV) has been found to diminish vir …
The clinical use of intravenous acyclovir.
Hopefl AW. Hopefl AW. Drug Intell Clin Pharm. 1983 Sep;17(9):623-8. doi: 10.1177/106002808301700902. Drug Intell Clin Pharm. 1983. PMID: 6311503 Review.
Acyclovir (acycloguanosine) is a new antiviral compound with activity against certain herpes viruses. Acyclovir is phosphorylated preferentially in virus-infected cells into its active form, acyclovir triphosphate, an inhibitor of viral-induced DNA polymerase
Acyclovir (acycloguanosine) is a new antiviral compound with activity against certain herpes viruses. Acyclovir is phosphoryla
Phase I clinical trial of valacyclovir and standard of care cyclophosphamide in children with endemic Burkitt lymphoma in Malawi.
Olson D, Gulley ML, Tang W, Wokocha C, Mechanic O, Hosseinipour M, Gold SH, Nguluwe N, Mwansambo C, Shores C. Olson D, et al. Clin Lymphoma Myeloma Leuk. 2013 Apr;13(2):112-8. doi: 10.1016/j.clml.2012.11.003. Epub 2012 Dec 20. Clin Lymphoma Myeloma Leuk. 2013. PMID: 23260601 Free PMC article. Clinical Trial.
Phase II efficacy trials should now be undertaken. BACKGROUND: Nucleoside analogues, including acyclovir, ganciclovir, and their precursors, have shown some efficacy against several Epstein-Barr virus (EBV)-associated diseases, including active EBV infection and posttransp …
Phase II efficacy trials should now be undertaken. BACKGROUND: Nucleoside analogues, including acyclovir, ganciclovir, and their prec …
Acyclovir. A review of its pharmacodynamic properties and therapeutic efficacy.
Richards DM, Carmine AA, Brogden RN, Heel RC, Speight TM, Avery GS. Richards DM, et al. Drugs. 1983 Nov;26(5):378-438. doi: 10.2165/00003495-198326050-00002. Drugs. 1983. PMID: 6315332 Review.
Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine. ...Acyclovir ointment demonstrated little benefit in recurrent genital herpes but topical acyclovir cream decreased the cours
Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine.
1,615 results