Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 3
1992 2
1993 4
1995 1
1996 3
1997 13
1998 20
1999 5
2000 7
2001 28
2002 10
2003 19
2004 15
2005 24
2006 21
2007 24
2008 28
2009 15
2010 19
2011 41
2012 34
2013 19
2014 35
2015 42
2016 33
2017 23
2018 28
2019 36
2020 26
2021 37
2022 40
2023 41
2024 53

Text availability

Article attribute

Article type

Publication date

Search Results

686 results

Results by year

Filters applied: . Clear all
Page 1
Managing acne vulgaris: an update.
Santer M, Burden-Teh E, Ravenscroft J. Santer M, et al. Drug Ther Bull. 2023 Dec 27;62(1):6-10. doi: 10.1136/dtb.2023.000051. Drug Ther Bull. 2023. PMID: 38154809 Free PMC article. Review.
Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide or topical retinoid (mainly adapalene) alone or in combination. Guidance published by the National Institute for Health and Care Excellence advis …
Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide or topical r …
Adapalene.
Tolaymat L, Dearborn H, Zito PM. Tolaymat L, et al. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29494115 Free Books & Documents.
Adapalene is a topical retinoid with FDA approval for treating acne vulgaris. Retinoids are vitamin A derivatives that are typically described in terms of generations with increased specificity of retinoic acid receptor (RAR) affinity with later generations. ...This activi …
Adapalene is a topical retinoid with FDA approval for treating acne vulgaris. Retinoids are vitamin A derivatives that are typically …
Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations.
Milosheska D, Roškar R. Milosheska D, et al. Adv Ther. 2022 Dec;39(12):5351-5375. doi: 10.1007/s12325-022-02319-7. Epub 2022 Oct 11. Adv Ther. 2022. PMID: 36220974 Free PMC article. Review.
Of the other retinoids contained in medicines, tazarotene and adapalene have clinically evaluated antiaging effects compared to tretinoin and may be considered as potential alternatives for antiaging treatments. ...
Of the other retinoids contained in medicines, tazarotene and adapalene have clinically evaluated antiaging effects compared to treti …
Novel and emerging treatment options for acne vulgaris.
Auffret N, Claudel JP, Leccia MT, Ballanger F, Dreno B. Auffret N, et al. Eur J Dermatol. 2022 Jul 1;32(4):451-458. doi: 10.1684/ejd.2022.4306. Eur J Dermatol. 2022. PMID: 36301760 Review. English.
Recently, in addition to other fixed combinations, a fixed combination of adapalene and benzoyl peroxide that targets acne scars has been made available for the first time. ...
Recently, in addition to other fixed combinations, a fixed combination of adapalene and benzoyl peroxide that targets acne scars has …
Adapalene.
[No authors listed] [No authors listed] 2023 May 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 May 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000483 Free Books & Documents. Review.
Topical adapalene has not been studied during breastfeeding. Because it is poorly absorbed after topical application, and blood levels are less than 0.25 mcg/L with long-term use, it is probably a low risk to the nursing infant.[1] Absorption should be minimized by applyin …
Topical adapalene has not been studied during breastfeeding. Because it is poorly absorbed after topical application, and blood level …
Topical Retinoids in Acne Vulgaris: A Systematic Review.
Kolli SS, Pecone D, Pona A, Cline A, Feldman SR. Kolli SS, et al. Am J Clin Dermatol. 2019 Jun;20(3):345-365. doi: 10.1007/s40257-019-00423-z. Am J Clin Dermatol. 2019. PMID: 30674002

Tretinoin 0.05% resulted in 62% of patients experiencing AEs compared with adapalene 0.1% (19%) and adapalene 0.3% (40%). More patients receiving adapalene were tolerant of the AEs compared with tazarotene (55.4% vs 24.4%; p < 0.0012). ...The differences i

…
Tretinoin 0.05% resulted in 62% of patients experiencing AEs compared with adapalene 0.1% (19%) and adapalene 0.3% (40%). More …
Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells.
Colucci M, Zumerle S, Bressan S, Gianfanti F, Troiani M, Valdata A, D'Ambrosio M, Pasquini E, Varesi A, Cogo F, Mosole S, Dongilli C, Desbats MA, Contu L, Revankdar A, Chen J, Kalathur M, Perciato ML, Basilotta R, Endre L, Schauer S, Othman A, Guccini I, Saponaro M, Maraccani L, Bancaro N, Lai P, Liu L, Pernigoni N, Mele F, Merler S, Trotman LC, Guarda G, Calì B, Montopoli M, Alimonti A. Colucci M, et al. Cancer Cell. 2024 Apr 8;42(4):646-661.e9. doi: 10.1016/j.ccell.2024.02.004. Epub 2024 Feb 29. Cancer Cell. 2024. PMID: 38428412 Free PMC article.
Here, we identify the retinoic-acid-receptor (RAR) agonist adapalene as an effective pro-senescence compound in prostate cancer (PCa). Reactivation of RARs triggers a robust senescence response and a tumor-suppressive SASP. In preclinical mouse models of PCa, the combinati …
Here, we identify the retinoic-acid-receptor (RAR) agonist adapalene as an effective pro-senescence compound in prostate cancer (PCa) …
Spotlight on adapalene.
Piérard GE, Piérard-Franchimont C, Paquet P, Quatresooz P. Piérard GE, et al. Expert Opin Drug Metab Toxicol. 2009 Dec;5(12):1565-75. doi: 10.1517/17425250903386269. Expert Opin Drug Metab Toxicol. 2009. PMID: 19929446 Review.
In acne, adapalene is expected to reduce comedogenesis, expel mature comedones and exert some anti-inflammatory effects. ...Clinical experience has established that adapalene represents a valuable addition to the other current treatments for acne....
In acne, adapalene is expected to reduce comedogenesis, expel mature comedones and exert some anti-inflammatory effects. ...Clinical …
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F. Liu H, et al. Cochrane Database Syst Rev. 2020 May 1;5(5):CD011368. doi: 10.1002/14651858.CD011368.pub2. Cochrane Database Syst Rev. 2020. PMID: 32356369 Free PMC article.
There may be little or no difference in PGA when comparing azelaic acid to clindamycin (RR 1.13, 95% CI 0.92 to 1.38; 1 study, 229 participants; low-quality evidence), but we are uncertain whether there is a difference between azelaic acid and adapalene (1 study, 55 partic …
There may be little or no difference in PGA when comparing azelaic acid to clindamycin (RR 1.13, 95% CI 0.92 to 1.38; 1 study, 229 participa …
686 results