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242 results

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Page 1
Guidelines of care for the management of acne vulgaris.
Reynolds RV, Yeung H, Cheng CE, Cook-Bolden F, Desai SR, Druby KM, Freeman EE, Keri JE, Stein Gold LF, Tan JKL, Tollefson MM, Weiss JS, Wu PA, Zaenglein AL, Han JM, Barbieri JS. Reynolds RV, et al. J Am Acad Dermatol. 2024 May;90(5):1006.e1-1006.e30. doi: 10.1016/j.jaad.2023.12.017. Epub 2024 Jan 30. J Am Acad Dermatol. 2024. PMID: 38300170
RESULTS: This guideline presents 18 evidence-based recommendations and 5 good practice statements. Strong recommendations are made for benzoyl peroxide, topical retinoids, topical antibiotics, and oral doxycycline. Oral isotretinoin is strongly recommended for acne …
RESULTS: This guideline presents 18 evidence-based recommendations and 5 good practice statements. Strong recommendations are made for be …
Management of Acne Vulgaris: A Review.
Eichenfield DZ, Sprague J, Eichenfield LF. Eichenfield DZ, et al. JAMA. 2021 Nov 23;326(20):2055-2067. doi: 10.1001/jama.2021.17633. JAMA. 2021. PMID: 34812859 Review.
Topical therapies such as retinoids (eg, tretinoin, adapalene), benzoyl peroxide, azelaic acid, and/or combinations of topical agents are first-line treatments. ...First-line therapies are topical retinoids, benzoyl peroxide, azelaic acid, or co …
Topical therapies such as retinoids (eg, tretinoin, adapalene), benzoyl peroxide, azelaic acid, and/or combinations of …
Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug.
Stein Gold L, Baldwin H, Kircik LH, Weiss JS, Pariser DM, Callender V, Lain E, Gold M, Beer K, Draelos Z, Sadick N, Pillai R, Bhatt V, Tanghetti EA. Stein Gold L, et al. Am J Clin Dermatol. 2022 Jan;23(1):93-104. doi: 10.1007/s40257-021-00650-3. Epub 2021 Oct 21. Am J Clin Dermatol. 2022. PMID: 34674160 Free PMC article. Clinical Trial.
OBJECTIVES: We aimed to evaluate the efficacy and safety of triple-combination, fixed-dose topical clindamycin phosphate 1.2%/benzoyl peroxide (BPO) 3.1%/adapalene 0.15% (IDP-126) gel for the treatment of acne. METHODS: In a phase II, double-blind, multicente …
OBJECTIVES: We aimed to evaluate the efficacy and safety of triple-combination, fixed-dose topical clindamycin phosphate 1.2%/benzoyl …
Managing acne vulgaris: an update.
Santer M, Burden-Teh E, Ravenscroft J. Santer M, et al. Drug Ther Bull. 2023 Dec 27;62(1):6-10. doi: 10.1136/dtb.2023.000051. Drug Ther Bull. 2023. PMID: 38154809 Free PMC article. Review.
Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide or topical retinoid (mainly adapalene) alone or in combination. Guidance published by the National Institute for Health and Care Ex …
Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide …
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F. Liu H, et al. Cochrane Database Syst Rev. 2020 May 1;5(5):CD011368. doi: 10.1002/14651858.CD011368.pub2. Cochrane Database Syst Rev. 2020. PMID: 32356369 Free PMC article.
In terms of total minor adverse events, we are uncertain if there is a difference between azelaic acid compared to adapalene (1 study; 55 participants) or benzoyl peroxide (1 study, 30 participants) (both very low-quality evidence). ...We are uncertain whethe …
In terms of total minor adverse events, we are uncertain if there is a difference between azelaic acid compared to adapalene (1 study …
Topical Retinoids in Acne Vulgaris: A Systematic Review.
Kolli SS, Pecone D, Pona A, Cline A, Feldman SR. Kolli SS, et al. Am J Clin Dermatol. 2019 Jun;20(3):345-365. doi: 10.1007/s40257-019-00423-z. Am J Clin Dermatol. 2019. PMID: 30674002

RESULTS: Topical retinoids are superior to vehicle in improving Investigator Global Assessment and Investigator's Static Global Assessment (24.1-28.8% and 13.3-17.3%, respectively; p < 0.001). A topical retinoid combined with benzoyl peroxide led to IGA improveme

…
RESULTS: Topical retinoids are superior to vehicle in improving Investigator Global Assessment and Investigator's Static Global Assessment ( …
Adapalene/benzoyl peroxide gel 0.3%/2.5% for acne vulgaris.
Dréno B, Layton AM, Troielli P, Rocha M, Chavda R. Dréno B, et al. Eur J Dermatol. 2022 Jul 1;32(4):445-450. doi: 10.1684/ejd.2022.4275. Eur J Dermatol. 2022. PMID: 36301750 Review. English.
Acne vulgaris is typically treated with a combination of a topical retinoid plus an antimicrobial agent, as recommended by national and international evidence-based guidelines around the globe. Adapalene, a synthetic topical retinoid, is available in two concentrations (0. …
Acne vulgaris is typically treated with a combination of a topical retinoid plus an antimicrobial agent, as recommended by national and inte …
Adapalene/Benzoyl Peroxide Gel 0.3%/2.5%: A Safe and Effective Acne Therapy in All Skin Phototypes.
Alexis AF, Cook-Bolden FE, York JP. Alexis AF, et al. J Drugs Dermatol. 2017 Jun 1;16(6):574-581. J Drugs Dermatol. 2017. PMID: 28686775 Clinical Trial.
This analysis investigated possible differences in the efficacy and safety of the fixed dose combination of 0.3% adapalene with 2.5% benzoyl peroxide (A/BPO gel 0.3%/2.5%) in subjects with Fitzpatrick Skin Types (FST) I-VI....
This analysis investigated possible differences in the efficacy and safety of the fixed dose combination of 0.3% adapalene with 2.5% …
Ceramide-Containing Adjunctive Skin Care for Skin Barrier Restoration During Acne Vulgaris Treatment.
Draelos ZD, Baalbaki N, Colon G, Dreno B. Draelos ZD, et al. J Drugs Dermatol. 2023 Jun 1;22(6):554-558. doi: 10.36849/JDD.7142. J Drugs Dermatol. 2023. PMID: 37276158 Clinical Trial.
Barrier damage caused by facial acne vulgaris can be magnified by topical medication, such as adapalene (0.3%) and benzoyl peroxide (2.5%)(A/BPO), which utilizes a retinoid to normalize follicular keratinization and BPO to decrease the C. acnes population. .. …
Barrier damage caused by facial acne vulgaris can be magnified by topical medication, such as adapalene (0.3%) and benzoyl …
Acne vulgaris: management.
[No authors listed] [No authors listed] London: National Institute for Health and Care Excellence (NICE); 2023 Dec 7. London: National Institute for Health and Care Excellence (NICE); 2023 Dec 7. PMID: 34424628 Free Books & Documents. Review.
242 results