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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1931 1
1934 1
1935 2
1938 1
1939 1
1942 2
1943 1
1945 5
1946 44
1947 37
1948 51
1949 35
1950 61
1951 96
1952 112
1953 166
1954 197
1955 165
1956 204
1957 226
1958 198
1959 233
1960 226
1961 316
1962 427
1963 845
1964 1319
1965 1300
1966 1489
1967 1830
1968 2106
1969 2447
1970 2653
1971 3583
1972 4395
1973 4248
1974 4576
1975 4594
1976 4296
1977 4383
1978 3719
1979 3749
1980 3910
1981 3764
1982 3880
1983 3893
1984 4319
1985 4669
1986 4561
1987 4390
1988 4597
1989 4973
1990 5261
1991 5417
1992 5513
1993 5789
1994 5980
1995 5844
1996 5836
1997 5843
1998 5729
1999 5730
2000 6225
2001 6129
2002 6123
2003 6247
2004 6366
2005 6300
2006 6488
2007 6451
2008 6373
2009 6587
2010 6841
2011 7140
2012 7311
2013 7672
2014 7529
2015 7556
2016 7078
2017 7265
2018 7179
2019 7442
2020 8312
2021 8276
2022 8994
2023 7198
2024 4232

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309,051 results

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Page 1
Adenosine-associated delivery systems.
Kazemzadeh-Narbat M, Annabi N, Tamayol A, Oklu R, Ghanem A, Khademhosseini A. Kazemzadeh-Narbat M, et al. J Drug Target. 2015;23(7-8):580-96. doi: 10.3109/1061186X.2015.1058803. J Drug Target. 2015. PMID: 26453156 Free PMC article. Review.
Adenosine is a naturally occurring purine nucleoside in every cell. ...In addition, due to adenosine's extremely short half-life in human blood (<10 s), there is an unmet need for sustained delivery systems to enhance efficacy and reduce side effects. ...
Adenosine is a naturally occurring purine nucleoside in every cell. ...In addition, due to adenosine's extremely short
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Wang P, Doxtader KA, Nam Y. Wang P, et al. Mol Cell. 2016 Jul 21;63(2):306-317. doi: 10.1016/j.molcel.2016.05.041. Epub 2016 Jun 30. Mol Cell. 2016. PMID: 27373337 Free PMC article.
How Mettl3 and Mettl14 cooperate to catalyze methylation of adenosines has remained elusive. We present crystal structures of the complex of Mettl3/Mettl14 methyltransferase domains in apo form as well as with bound S-adenosylmethionine (SAM) or S-adenosylhomocysteine (SAH …
How Mettl3 and Mettl14 cooperate to catalyze methylation of adenosines has remained elusive. We present crystal structures of the com …
[Adenosine and its role in physiology].
Novotný J. Novotný J. Cesk Fysiol. 2015;64(1):35-44. Cesk Fysiol. 2015. PMID: 26738245 Review. Slovak.
Adenosine is formed by enzymatic degradation of adenosine triphosphate and eliminated by phosphorylation to adenosine monophosphate or by deamination to inosine. ...Extracellular adenosine as a signaling molecule binds to adenosine receptors, wh
Adenosine is formed by enzymatic degradation of adenosine triphosphate and eliminated by phosphorylation to adenosine m
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.
Lewis BP, Burge CB, Bartel DP. Lewis BP, et al. Cell. 2005 Jan 14;120(1):15-20. doi: 10.1016/j.cell.2004.12.035. Cell. 2005. PMID: 15652477 Free article.
We predict regulatory targets of vertebrate microRNAs (miRNAs) by identifying mRNAs with conserved complementarity to the seed (nucleotides 2-7) of the miRNA. An overrepresentation of conserved adenosines flanking the seed complementary sites in mRNAs indicates that primar …
We predict regulatory targets of vertebrate microRNAs (miRNAs) by identifying mRNAs with conserved complementarity to the seed (nucleotides …
Adenosine.
O'Rangers EA. O'Rangers EA. Conn Med. 1990 Nov;54(11):635-6. Conn Med. 1990. PMID: 2261769 Review. No abstract available.
The adenosine-mediated, neuronal-glial, homeostatic sleep response.
Greene RW, Bjorness TE, Suzuki A. Greene RW, et al. Curr Opin Neurobiol. 2017 Jun;44:236-242. doi: 10.1016/j.conb.2017.05.015. Epub 2017 Jun 19. Curr Opin Neurobiol. 2017. PMID: 28633050 Free PMC article. Review.
This sleep-homeostasis related SWA results from a buildup and decay of extracellular adenosine that acts at neuronal adenosine A1 receptors to facilitate SWA and is metabolized by adenosine kinase found in glia. This local neuronal-glial circuit for homeostat …
This sleep-homeostasis related SWA results from a buildup and decay of extracellular adenosine that acts at neuronal adenosine
AZD6140.
Tantry US, Bliden KP, Gurbel PA. Tantry US, et al. Expert Opin Investig Drugs. 2007 Feb;16(2):225-9. doi: 10.1517/13543784.16.2.225. Expert Opin Investig Drugs. 2007. PMID: 17243942 Review.
Adenosine in exercise adaptation.
Simpson RE, Phillis JW. Simpson RE, et al. Br J Sports Med. 1992 Mar;26(1):54-8. doi: 10.1136/bjsm.26.1.54. Br J Sports Med. 1992. PMID: 1600457 Free PMC article. Review.
However, adenosine's possible influence over the vasodilatory response to exercise in skeletal muscle is controversial and more research is required to resolve this issue. Various popular exercise training methods, such as cyclic training, interval training, and the …
However, adenosine's possible influence over the vasodilatory response to exercise in skeletal muscle is controversial and mor …
Adenosine receptor ligands in clinical trials.
Rizzolio F, La Montagna R, Tuccinardi T, Russo G, Caputi M, Giordano A. Rizzolio F, et al. Curr Top Med Chem. 2010;10(10):1036-45. doi: 10.2174/156802610791293154. Curr Top Med Chem. 2010. PMID: 20370654 Review.
Adenosine and its receptors play different roles in normal and patho-physiological conditions. ...Engineered mice have helped to dissect the single adenosine receptor function in specific tissues and pathological conditions. ...
Adenosine and its receptors play different roles in normal and patho-physiological conditions. ...Engineered mice have helped to diss
309,051 results
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