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Year Number of Results
1931 1
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1935 2
1938 1
1939 1
1942 2
1943 1
1945 5
1946 44
1947 37
1948 51
1949 35
1950 61
1951 96
1952 112
1953 166
1954 197
1955 165
1956 204
1957 226
1958 198
1959 233
1960 226
1961 316
1962 427
1963 845
1964 1319
1965 1300
1966 1489
1967 1830
1968 2106
1969 2447
1970 2653
1971 3583
1972 4395
1973 4248
1974 4576
1975 4594
1976 4296
1977 4383
1978 3719
1979 3749
1980 3910
1981 3764
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1983 3893
1984 4319
1985 4669
1986 4562
1987 4390
1988 4597
1989 4973
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1992 5513
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1994 5980
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1996 5836
1997 5843
1998 5729
1999 5730
2000 6225
2001 6130
2002 6123
2003 6247
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2005 6300
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2007 6451
2008 6373
2009 6587
2010 6841
2011 7140
2012 7311
2013 7672
2014 7529
2015 7556
2016 7078
2017 7268
2018 7178
2019 7442
2020 8314
2021 8303
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2023 7279
2024 7982
2025 6735
2026 36

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318,729 results

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Page 1
Adenosine-associated delivery systems.
Kazemzadeh-Narbat M, Annabi N, Tamayol A, Oklu R, Ghanem A, Khademhosseini A. Kazemzadeh-Narbat M, et al. J Drug Target. 2015;23(7-8):580-96. doi: 10.3109/1061186X.2015.1058803. J Drug Target. 2015. PMID: 26453156 Free PMC article. Review.
Adenosine is a naturally occurring purine nucleoside in every cell. Many critical treatments such as modulating irregular heartbeat (arrhythmias), regulation of central nervous system (CNS) activity and inhibiting seizural episodes can be carried out using adenosine …
Adenosine is a naturally occurring purine nucleoside in every cell. Many critical treatments such as modulating irregular heartbeat ( …
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Wang P, Doxtader KA, Nam Y. Wang P, et al. Mol Cell. 2016 Jul 21;63(2):306-317. doi: 10.1016/j.molcel.2016.05.041. Epub 2016 Jun 30. Mol Cell. 2016. PMID: 27373337 Free PMC article.
How Mettl3 and Mettl14 cooperate to catalyze methylation of adenosines has remained elusive. We present crystal structures of the complex of Mettl3/Mettl14 methyltransferase domains in apo form as well as with bound S-adenosylmethionine (SAM) or S-adenosylhomocysteine (SAH …
How Mettl3 and Mettl14 cooperate to catalyze methylation of adenosines has remained elusive. We present crystal structures of the com …
Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism.
Ogawa A, Watanabe S, Ozerova I, Tsai AY, Kuchitsu Y, Chong HB, Kawakami T, Fuse J, Han W, Kudo R, Naito T, Sato K, Nakazawa T, Saheki Y, Hirayama A, Stadler PF, Arisawa M, Araki K, Bar-Peled L, Taguchi T, Sawa S, Inaba K, Wei FY. Ogawa A, et al. Cell. 2025 Oct 30;188(22):6151-6169.e24. doi: 10.1016/j.cell.2025.07.041. Epub 2025 Aug 20. Cell. 2025. PMID: 40840445 Free article.
After phosphorylation by adenosine kinase (ADK), they undergo deamination by adenosine deaminase-like (ADAL). In Adal knockout mice, N(6)-modified adenosine monophosphates (AMPs) accumulate and allosterically inhibit AMP-activated protein kinase (AMPK), dysre …
After phosphorylation by adenosine kinase (ADK), they undergo deamination by adenosine deaminase-like (ADAL). In Adal knockout …
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.
Lewis BP, Burge CB, Bartel DP. Lewis BP, et al. Cell. 2005 Jan 14;120(1):15-20. doi: 10.1016/j.cell.2004.12.035. Cell. 2005. PMID: 15652477 Free article.
We predict regulatory targets of vertebrate microRNAs (miRNAs) by identifying mRNAs with conserved complementarity to the seed (nucleotides 2-7) of the miRNA. An overrepresentation of conserved adenosines flanking the seed complementary sites in mRNAs indicates that primar …
We predict regulatory targets of vertebrate microRNAs (miRNAs) by identifying mRNAs with conserved complementarity to the seed (nucleotides …
The adenosine-mediated, neuronal-glial, homeostatic sleep response.
Greene RW, Bjorness TE, Suzuki A. Greene RW, et al. Curr Opin Neurobiol. 2017 Jun;44:236-242. doi: 10.1016/j.conb.2017.05.015. Epub 2017 Jun 19. Curr Opin Neurobiol. 2017. PMID: 28633050 Free PMC article. Review.
This sleep-homeostasis related SWA results from a buildup and decay of extracellular adenosine that acts at neuronal adenosine A1 receptors to facilitate SWA and is metabolized by adenosine kinase found in glia. This local neuronal-glial circuit for homeostat …
This sleep-homeostasis related SWA results from a buildup and decay of extracellular adenosine that acts at neuronal adenosine …
[Adenosine and its role in physiology].
Novotný J. Novotný J. Cesk Fysiol. 2015;64(1):35-44. Cesk Fysiol. 2015. PMID: 26738245 Review. Slovak.
Adenosine is formed by enzymatic degradation of adenosine triphosphate and eliminated by phosphorylation to adenosine monophosphate or by deamination to inosine. ...Extracellular adenosine as a signaling molecule binds to adenosine receptors, wh …
Adenosine is formed by enzymatic degradation of adenosine triphosphate and eliminated by phosphorylation to adenosine m …
Adenosine as a Key Mediator of Neuronal Survival in Cerebral Ischemic Injury.
Khan H, Kaur P, Singh TG, Grewal AK, Sood S. Khan H, et al. Neurochem Res. 2022 Dec;47(12):3543-3555. doi: 10.1007/s11064-022-03737-3. Epub 2022 Aug 30. Neurochem Res. 2022. PMID: 36042141 Review.
Several experimental studies have linked adenosine's neuroprotective role in cerebral ischemia. During ischemia, adenosine is formed due to intracellular ATP breakdown into ADP, further when phosphate is released from ADP, the adenosine monophosphate i …
Several experimental studies have linked adenosine's neuroprotective role in cerebral ischemia. During ischemia, adenosine …
How RNA editing keeps an I on physiology.
Goldeck M, Gopal A, Jantsch MF, Mansouri Khosravi HR, Rajendra V, Vesely C. Goldeck M, et al. Am J Physiol Cell Physiol. 2022 Nov 1;323(5):C1496-C1511. doi: 10.1152/ajpcell.00191.2022. Epub 2022 Aug 29. Am J Physiol Cell Physiol. 2022. PMID: 36036447 Free article. Review.
Adenosine deaminases acting on RNAs convert adenosines (A) to inosines (I) in structured or double-stranded RNAs. ...In the human transcriptome, more than a million different sites have been identified that undergo an ADAR-mediated A-to-I exchange Inosines have an a …
Adenosine deaminases acting on RNAs convert adenosines (A) to inosines (I) in structured or double-stranded RNAs. ...In the hu …
Synthesis of 1'-C-fluoromethyladenosine.
Damont A, Dukhan D, Gosselin G, Peyronnet J, Storer R. Damont A, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1431-4. doi: 10.1080/15257770701542165. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066799
Adenosine: The common target between cancer immunotherapy and glaucoma in the eye.
Hallaj S, Mirza-Aghazadeh-Attari M, Arasteh A, Ghorbani A, Lee D, Jadidi-Niaragh F. Hallaj S, et al. Life Sci. 2021 Oct 1;282:119796. doi: 10.1016/j.lfs.2021.119796. Epub 2021 Jul 8. Life Sci. 2021. PMID: 34245774 Review.
Several studies have elucidated Adenosine's effect and its up-and downstream molecules and enzymes on the anti-tumor response against several types of cancers. ...Glaucoma is the second leading cause of blindness globally, and the recent application of Adenosine …
Several studies have elucidated Adenosine's effect and its up-and downstream molecules and enzymes on the anti-tumor response …
318,729 results
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