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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 3
1981 5
1982 5
1983 14
1984 12
1985 21
1986 26
1987 22
1988 29
1989 21
1990 39
1991 39
1992 31
1993 31
1994 32
1995 25
1996 17
1997 19
1998 28
1999 21
2000 14
2001 8
2002 7
2003 17
2004 11
2005 21
2006 10
2007 15
2008 9
2009 12
2010 4
2011 10
2012 9
2013 3
2014 12
2015 10
2016 5
2017 6
2018 6
2019 7
2020 5
2021 4
2022 0
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628 results
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Page 1
Alprazolam as an antidepressant.
Warner MD, Peabody CA, Whiteford HA, Hollister LE. Warner MD, et al. J Clin Psychiatry. 1988 Apr;49(4):148-50. J Clin Psychiatry. 1988. PMID: 3281931 Review.
Alprazolam appears to be an effective antidepressant in the treatment of outpatients who have a diagnosis of major depressive disorder. ...No satisfactory explanation exists for the mechanism of alprazolam's proposed antidepressant action....
Alprazolam appears to be an effective antidepressant in the treatment of outpatients who have a diagnosis of major depressive disorde
Inhaled alprazolam rapidly suppresses epileptic activity in photosensitive participants.
French JA, Wechsler R, Gelfand MA, Pollard JR, Vazquez B, Friedman D, Gong LH, Kamemoto E, Isojarvi J, Cassella JV. French JA, et al. Epilepsia. 2019 Aug;60(8):1602-1609. doi: 10.1111/epi.16279. Epub 2019 Jul 3. Epilepsia. 2019. PMID: 31268555 Clinical Trial.
The AE profile of Staccato alprazolam was similar to what has been reported for alprazolam for other indications. The results support further development of Staccato alprazolam as a rescue medication for the acute treatment of seizures....
The AE profile of Staccato alprazolam was similar to what has been reported for alprazolam for other indications. The results …
A randomized clinical trial of alprazolam versus progressive muscle relaxation in cancer patients with anxiety and depressive symptoms.
Holland JC, Morrow GR, Schmale A, Derogatis L, Stefanek M, Berenson S, Carpenter PJ, Breitbart W, Feldstein M. Holland JC, et al. J Clin Oncol. 1991 Jun;9(6):1004-11. doi: 10.1200/JCO.1991.9.6.1004. J Clin Oncol. 1991. PMID: 2033413 Clinical Trial.
A randomized nonblinded study was performed in three cancer centers to test over a 10-day period the efficacy of (1) a triazolobenzodiazepine, alprazolam, 0.5 mg three times a day and (2) use of a behavioral technique in which patients were trained in progressive muscle re …
A randomized nonblinded study was performed in three cancer centers to test over a 10-day period the efficacy of (1) a triazolobenzodiazepin …
Panic disorder: long-term pharmacotherapy and discontinuation.
Rickels K, Schweizer E. Rickels K, et al. J Clin Psychopharmacol. 1998 Dec;18(6 Suppl 2):12S-18S. doi: 10.1097/00004714-199812001-00004. J Clin Psychopharmacol. 1998. PMID: 9872708 Review.
One hundred six PD patients were enrolled in a double-blind, 8-month, placebo-controlled trial of alprazolam and imipramine. In the 8-week short-term phase, daily dosages were titrated up to 10 mg/day of alprazolam and 250 mg/day of imipramine. ...In the 6-month mai …
One hundred six PD patients were enrolled in a double-blind, 8-month, placebo-controlled trial of alprazolam and imipramine. In the 8 …
Pharmacodynamic response profiles of anxiolytic and sedative drugs.
Chen X, Broeyer F, de Kam M, Baas J, Cohen A, van Gerven J. Chen X, et al. Br J Clin Pharmacol. 2017 May;83(5):1028-1038. doi: 10.1111/bcp.13204. Epub 2017 Mar 17. Br J Clin Pharmacol. 2017. PMID: 27922194 Free PMC article. Clinical Trial.
RESULTS: Compared to placebo, VAS(calmness) increased with alprazolam (2.0 mm) and pregabalin (2.5 mm) but not with diphenhydramine. Saccadic peak velocity (SPV) declined after alprazolam (-57 s(-1) ) and pregabalin (-28 s(-1) ), more than with diphenh …
RESULTS: Compared to placebo, VAS(calmness) increased with alprazolam (2.0 mm) and pregabalin (2.5 mm) but not with diphenhydramine. …
Effects of Oral Administration of Alprazolam and Lorazepam as Hypnotics on Cardiovascular Parameters in Hypertensive Patients.
Costa A, D'Angelo A, Ramusino MC, Perini G, Bosone D, Derosa G, Fogari R. Costa A, et al. J Clin Psychopharmacol. 2021 Mar-Apr 01;41(2):191-195. doi: 10.1097/JCP.0000000000001362. J Clin Psychopharmacol. 2021. PMID: 33587402 Clinical Trial.

The aim of this study was to compare the effect of chronic oral administration of alprazolam and lorazepam as hypnotics on ambulatory BP and HR in patients with mild hypertension. ...Nocturnal HR mean values were significantly increased by lorazepam (+10.1%, P < 0.01 vs

The aim of this study was to compare the effect of chronic oral administration of alprazolam and lorazepam as hypnotics on ambulatory …
Human abuse potential of brivaracetam in healthy recreational central nervous system depressant users.
Schoedel KA, Stockis A, Sellers EM. Schoedel KA, et al. Epilepsy Behav. 2018 Jan;78:194-201. doi: 10.1016/j.yebeh.2017.09.008. Epub 2017 Nov 15. Epilepsy Behav. 2018. PMID: 29153631 Clinical Trial.
Brivaracetam 1000mg had significantly higher Overall Drug Liking VAS E(max) than alprazolam 1.5mg, but was not significantly different from alprazolam 3mg. Feeling High VAS E(max) was lower versus alprazolam with brivaracetam 50 and 200mg, while brivaracetam …
Brivaracetam 1000mg had significantly higher Overall Drug Liking VAS E(max) than alprazolam 1.5mg, but was not significantly differen …
Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression.
Dawson GW, Jue SG, Brogden RN. Dawson GW, et al. Drugs. 1984 Feb;27(2):132-47. doi: 10.2165/00003495-198427020-00002. Drugs. 1984. PMID: 6141930 Review.
Relative to the newer benzodiazepines, alprazolam has an intermediate half-life of 10 to 12 hours in healthy young subjects. ...Thus, alprazolam may be particularly useful in patients with mixed anxiety/depression. ...
Relative to the newer benzodiazepines, alprazolam has an intermediate half-life of 10 to 12 hours in healthy young subjects. ...Thus, …
Evaluating drugged driving: Effects of exemplar pain and anxiety medications.
Brown TL, Milavetz G, Gaffney G, Spurgin A. Brown TL, et al. Traffic Inj Prev. 2018 Feb 28;19(sup1):S97-S103. doi: 10.1080/15389588.2017.1378814. Traffic Inj Prev. 2018. PMID: 29584496 Clinical Trial.
Using a double-blind, placebo-controlled crossover design, we administered placebo, alprazolam alone, hydrocodone/acetaminophen, and the combination of the 2 drugs in a standardized simulated driving protocol. Measures of lateral and longitudinal control were collected and …
Using a double-blind, placebo-controlled crossover design, we administered placebo, alprazolam alone, hydrocodone/acetaminophen, and …
628 results