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12,545 results

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Page 1
Amiloride and calciuria.
Luft FC, Sällström J. Luft FC, et al. Nephrol Dial Transplant. 2022 Jan 25;37(2):205-207. doi: 10.1093/ndt/gfab221. Nephrol Dial Transplant. 2022. PMID: 34264323 No abstract available.
Amiloride: A review.
Sun Q, Sever P. Sun Q, et al. J Renin Angiotensin Aldosterone Syst. 2020 Oct-Dec;21(4):1470320320975893. doi: 10.1177/1470320320975893. J Renin Angiotensin Aldosterone Syst. 2020. PMID: 33234024 Free PMC article. Review.
Amiloride is a potassium retaining diuretic and natriuretic which acts by reversibly blocking luminal epithelial sodium channels (ENaCs) in the late distal tubule and collecting duct. Amiloride is indicated in oedematous states, and for potassium conservation adjunc …
Amiloride is a potassium retaining diuretic and natriuretic which acts by reversibly blocking luminal epithelial sodium channels (ENa …
Amiloride-induced hyponatremia.
Tarssanen L, Huikko M, Rossi M. Tarssanen L, et al. Acta Med Scand. 1980;208(6):491-4. doi: 10.1111/j.0954-6820.1980.tb01236.x. Acta Med Scand. 1980. PMID: 7468318
We present three aged female patients who fulfil the criteria of a syndrome that we call "amiloride hyponatremia". They became hyponatremic during amiloride + hydrochlorothiazide therapy. ..."Amiloride hyponatremia" is suggested to be due to a direct effect o …
We present three aged female patients who fulfil the criteria of a syndrome that we call "amiloride hyponatremia". They became hypona …
Amiloride alleviates morphine tolerance by suppressing ASIC3-dependent neuroinflammation in the spinal cord.
Gei L, Yan Y, Xing W, Li Q, Chen X, Yan F, Wang Y, Cao Y, Jiang W, E R, Luo D, Zhang Y, Zeng W, Chen D. Gei L, et al. Eur J Pharmacol. 2024 Jan 15;963:176173. doi: 10.1016/j.ejphar.2023.176173. Epub 2023 Oct 31. Eur J Pharmacol. 2024. PMID: 37918499 Free article.
Microglia play a crucial role in the establishment of morphine tolerance. Thus, we anticipated that amiloride might suppress the development of morphine tolerance. During this investigation, we assessed the impact of amiloride on mouse morphine tolerance. ...Further …
Microglia play a crucial role in the establishment of morphine tolerance. Thus, we anticipated that amiloride might suppress the deve …
Amiloride Analogs as ASIC1a Inhibitors.
Leng TD, Si HF, Li J, Yang T, Zhu M, Wang B, Simon RP, Xiong ZG. Leng TD, et al. CNS Neurosci Ther. 2016 Jun;22(6):468-76. doi: 10.1111/cns.12524. Epub 2016 Feb 18. CNS Neurosci Ther. 2016. PMID: 26890278 Free PMC article.
Surflex-Dock was used to dock the analogs into the pocket with default parameters. RESULTS: Amiloride and its analogs inhibit ASIC1a currents expressed in Chinese hamster ovary cells with a potency rank order of benzamil > phenamil > 5-(N,N-dimethyl)amiloride …
Surflex-Dock was used to dock the analogs into the pocket with default parameters. RESULTS: Amiloride and its analogs inhibit ASIC1a …
Amiloride and its analogs as tools in the study of ion transport.
Kleyman TR, Cragoe EJ Jr. Kleyman TR, et al. J Membr Biol. 1988 Oct;105(1):1-21. doi: 10.1007/BF01871102. J Membr Biol. 1988. PMID: 2852254 Review.
Amiloride inhibits most plasma membrane Na+ transport systems. We have reviewed the pharmacology of inhibition of these transporters by amiloride and its analogs. ...The availability of radioactive and photoactive amiloride analogs, anti-amiloride anti …
Amiloride inhibits most plasma membrane Na+ transport systems. We have reviewed the pharmacology of inhibition of these transporters …
Amiloride in primary hyperaldosteronism.
Griffing GT, Cole AG, Aurecchia SA, Sindler BH, Komanicky P, Melby JC. Griffing GT, et al. Clin Pharmacol Ther. 1982 Jan;31(1):56-61. doi: 10.1038/clpt.1982.9. Clin Pharmacol Ther. 1982. PMID: 7053305
Amiloride is a potassium-sparing diuretic used in spontaneous and diuretic-induced hypokalemia. ...Our study demonstrates the efficacy of amiloride in the correction of hypokalemia and amelioration of hypertension in primary hyperaldosteronism....
Amiloride is a potassium-sparing diuretic used in spontaneous and diuretic-induced hypokalemia. ...Our study demonstrates the efficac …
Allosteric modulation of G protein-coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?
Massink A, Amelia T, Karamychev A, IJzerman AP. Massink A, et al. Med Res Rev. 2020 Mar;40(2):683-708. doi: 10.1002/med.21633. Epub 2019 Sep 8. Med Res Rev. 2020. PMID: 31495942 Free PMC article. Review.
Amiloride analogs with lipophilic substituents tend to be more potent modulators than amiloride itself. Adenosine, alpha-adrenergic and dopamine receptors are most strongly modulated by amiloride analogs. In addition, for a few GPCRs, more than one binding si …
Amiloride analogs with lipophilic substituents tend to be more potent modulators than amiloride itself. Adenosine, alpha-adren …
Stability of extemporaneously compounded amiloride nasal spray.
Yellepeddi V, Sayre C, Burrows A, Watt K, Davies S, Strauss J, Battaglia M. Yellepeddi V, et al. PLoS One. 2020 Jul 10;15(7):e0232435. doi: 10.1371/journal.pone.0232435. eCollection 2020. PLoS One. 2020. PMID: 32649677 Free PMC article.
Therefore, this study reports the formulation, physical, chemical, and microbiological stability of an extemporaneously prepared amiloride 2 mg/mL nasal spray. The amiloride nasal spray was prepared by adding 100 mg of amiloride hydrochloride to 50 mL of ster …
Therefore, this study reports the formulation, physical, chemical, and microbiological stability of an extemporaneously prepared amilorid …
Topology of an amiloride-binding protein.
Lin C, Kieber-Emmons T, Villalobos AP, Foster MH, Wahlgren C, Kleyman TR. Lin C, et al. J Biol Chem. 1994 Jan 28;269(4):2805-13. J Biol Chem. 1994. PMID: 8300613 Free article.
We have previously raised and characterized a monoclonal antiamiloride antibody (mAb BA7.1) which is similar to epithelial Na+ channels in its specificity of binding of amiloride and amiloride analogs, suggesting that their amiloride binding sites may be simi …
We have previously raised and characterized a monoclonal antiamiloride antibody (mAb BA7.1) which is similar to epithelial Na+ channels in i …
12,545 results
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