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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 12
1966 12
1967 27
1968 22
1969 23
1970 24
1971 30
1972 26
1973 33
1974 37
1975 24
1976 36
1977 28
1978 46
1979 32
1980 40
1981 38
1982 52
1983 41
1984 40
1985 48
1986 44
1987 26
1988 43
1989 48
1990 32
1991 32
1992 33
1993 29
1994 32
1995 33
1996 34
1997 22
1998 28
1999 19
2000 24
2001 22
2002 33
2003 28
2004 18
2005 24
2006 18
2007 24
2008 22
2009 27
2010 17
2011 20
2012 15
2013 24
2014 18
2015 15
2016 18
2017 18
2018 12
2019 2
2020 8
2021 6
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1,498 results
Results by year
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Page 1
Randomised clinical trial comparing melatonin 3 mg, amitriptyline 25 mg and placebo for migraine prevention.
Gonçalves AL, Martini Ferreira A, Ribeiro RT, Zukerman E, Cipolla-Neto J, Peres MF. Gonçalves AL, et al. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1127-32. doi: 10.1136/jnnp-2016-313458. Epub 2016 May 10. J Neurol Neurosurg Psychiatry. 2016. PMID: 27165014 Free PMC article. Clinical Trial.
Melatonin was better tolerated than amitriptyline. Weight loss was found in the melatonin group, a slight weight gain in placebo and significantly for amitriptyline users. CONCLUSIONS: Melatonin 3 mg is better than placebo for migraine prevention, more tolerable tha …
Melatonin was better tolerated than amitriptyline. Weight loss was found in the melatonin group, a slight weight gain in placebo and …
Clinical activity and tolerability of trazodone, mianserin, and amitriptyline in elderly subjects with major depression: a controlled multicenter trial.
Altamura AC, Mauri MC, Rudas N, Carpiniello B, Montanini R, Perini M, Scapicchio PL, Hadjchristos C, Carucci G, Minervini M, et al. Altamura AC, et al. Clin Neuropharmacol. 1989;12 Suppl 1:S25-33; S34-7. doi: 10.1097/00002826-198901001-00005. Clin Neuropharmacol. 1989. PMID: 2663151 Clinical Trial.
The aim of this multicenter study was to compare trazodone (TRA) with two reference drugs, amitriptyline (AMI) and mianserin (MIA), under double-blind conditions, in an elderly population, to ascertain age-related patterns for efficacy and tolerability. ...
The aim of this multicenter study was to compare trazodone (TRA) with two reference drugs, amitriptyline (AMI) and mianserin (MIA), u …
Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial.
Carette S, Bell MJ, Reynolds WJ, Haraoui B, McCain GA, Bykerk VP, Edworthy SM, Baron M, Koehler BE, Fam AG, et al. Carette S, et al. Arthritis Rheum. 1994 Jan;37(1):32-40. doi: 10.1002/art.1780370106. Arthritis Rheum. 1994. PMID: 8129762 Clinical Trial.
OBJECTIVE: To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia, and to identify predictors of response to amitriptyline and cyclobenzaprine. METHODS: Two hundred eight patients who fulfill …
OBJECTIVE: To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibro …
A comparative clinical trial of mianserin (Norval) and amitriptyline in the treatment of depression in general practice.
Murphy JE, Bridgman KM. Murphy JE, et al. J Int Med Res. 1978;6(3):199-206. doi: 10.1177/030006057800600306. J Int Med Res. 1978. PMID: 348535 Free article. Clinical Trial.
A double-blind controlled comparative trial of mianserin (Norval) and amitriptyline was conducted in general practice. Fifty-one patients were treated with amitriptyline and fifty-five with mianserin. The dosage for the first week was 25 mg t.d.s. for amit
A double-blind controlled comparative trial of mianserin (Norval) and amitriptyline was conducted in general practice. Fifty-one pati …
Assessment of adverse events in clinical drug trials: Identifying amitriptyline's placebo- and baseline-controlled side effects.
Rheker J, Rief W, Doering BK, Winkler A. Rheker J, et al. Exp Clin Psychopharmacol. 2018 Jun;26(3):320-326. doi: 10.1037/pha0000194. Exp Clin Psychopharmacol. 2018. PMID: 29863388 Clinical Trial.
Frequency of complaints and their intensity were compared after medication intake between the two groups while controlling for complaints at baseline. The amitriptyline group's participants reported having suffered from "dry mouth," "dizziness," "subjective blood ci …
Frequency of complaints and their intensity were compared after medication intake between the two groups while controlling for complaints at …
Pharmacokinetics of intravenous and oral amitriptyline and its active metabolite nortriptyline in Greyhound dogs.
Norkus C, Rankin D, KuKanich B. Norkus C, et al. Vet Anaesth Analg. 2015 Nov;42(6):580-9. doi: 10.1111/vaa.12248. Epub 2015 Feb 14. Vet Anaesth Analg. 2015. PMID: 25683584 Clinical Trial.
OBJECTIVE: To evaluate the pharmacokinetics of amitriptyline and its active metabolite nortriptyline after intravenous (IV) and oral amitriptyline administration in healthy dogs. ...CONCLUSIONS AND CLINICAL RELEVANCE: Amitriptyline at 4 mg kg(-1) administered …
OBJECTIVE: To evaluate the pharmacokinetics of amitriptyline and its active metabolite nortriptyline after intravenous (IV) and oral …
Bioequivalence Study of Amitriptyline Hydrochloride Tablets in Healthy Chinese Volunteers Under Fasting and Fed Conditions.
Zhai Y, Wu L, Zheng Y, Wu M, Huang Y, Huang Q, Shentu J, Zhao Q, Liu J. Zhai Y, et al. Drug Des Devel Ther. 2020 Aug 4;14:3131-3142. doi: 10.2147/DDDT.S258173. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 32801649 Free PMC article. Clinical Trial.
PURPOSE: This study compares the pharmacokinetic and safety profiles between a new generic and a branded reference formulation of amitriptyline hydrochloride tablets, and assesses the bioequivalence of the two products in healthy Chinese volunteers to obtain sufficient evi …
PURPOSE: This study compares the pharmacokinetic and safety profiles between a new generic and a branded reference formulation of amitrip
Clinical response and plasma concentration of amitriptyline and its metabolite nortriptyline.
Vandel S, Vandel B, Sandoz M, Allers G, Bechtel P, Volmat R. Vandel S, et al. Eur J Clin Pharmacol. 1978 Nov 27;14(3):185-90. doi: 10.1007/BF02089958. Eur J Clin Pharmacol. 1978. PMID: 365538 Clinical Trial.
Plasma levels of amitriptyline and nortriptyline were measured twice weekly in 62 patients treated for three weeks with i.m. amitriptyline 120 mg/day. In half the patients the ratio of amitriptyline to nortriptyline was under 1 and in the other half it was gr …
Plasma levels of amitriptyline and nortriptyline were measured twice weekly in 62 patients treated for three weeks with i.m. amitr
A clinical trial comparing sustained release amitryptyline (Saroten Retard) and conventional amitriptyline tablets (Saroten) in endogenously depressed patients with simultaneous determination of serum levels of amitryptyline and nortriptyline.
Liisberg P, Mose H, Amdisen A, Jørgensen A, Petersen HE. Liisberg P, et al. Acta Psychiatr Scand. 1978 May;57(5):426-35. doi: 10.1111/j.1600-0447.1978.tb06911.x. Acta Psychiatr Scand. 1978. PMID: 354330 Clinical Trial.
The clinical effect of a sustained release preparation of amitriptyline has been compared with that of conventional amitriptyline tablets in a double-blind cross-over study with 24 patients suffering from endogenous depression. ...No correlation could be shown betwe …
The clinical effect of a sustained release preparation of amitriptyline has been compared with that of conventional amitriptyline
Clinical response and plasma concentrations of amitriptyline and its metabolite-nortriptyline in depressive patients.
Miljković B, Pokrajac M, Timotijević I, Varagić V. Miljković B, et al. Eur J Drug Metab Pharmacokinet. 1996 Jul-Sep;21(3):251-5. doi: 10.1007/BF03189722. Eur J Drug Metab Pharmacokinet. 1996. PMID: 8980924 Clinical Trial.
Although many attempts have been made, to date no convincing evidence exists of a relationship between plasma concentrations of amitriptyline (AT), its active metabolite nortriptyline (NT) and clinical response. ...
Although many attempts have been made, to date no convincing evidence exists of a relationship between plasma concentrations of amitripty
1,498 results