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2024 188

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Page 1
Oral amoxicillin and amoxicillin-clavulanic acid: properties, indications and usage.
Huttner A, Bielicki J, Clements MN, Frimodt-Møller N, Muller AE, Paccaud JP, Mouton JW. Huttner A, et al. Clin Microbiol Infect. 2020 Jul;26(7):871-879. doi: 10.1016/j.cmi.2019.11.028. Epub 2019 Dec 4. Clin Microbiol Infect. 2020. PMID: 31811919 Free article. Review.
OBJECTIVES: In this narrative review, we re-examine the properties of oral amoxicillin and clavulanic acid and provide guidance on their use, with emphasis on the preferred use of amoxicillin alone. SOURCES: Published medical literature (MEDLINE databa …
OBJECTIVES: In this narrative review, we re-examine the properties of oral amoxicillin and clavulanic acid and provide …
Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial.
Keij FM, Kornelisse RF, Hartwig NG, van der Sluijs-Bens J, van Beek RHT, van Driel A, van Rooij LGM, van Dalen-Vink I, Driessen GJA, Kenter S, von Lindern JS, Eijkemans M, Stam-Stigter GM, Qi H, van den Berg MM, Baartmans MGA, van der Meer-Kappelle LH, Meijssen CB, Norbruis OF, Heidema J, van Rossem MC, den Butter PCP, Allegaert K, Reiss IKM, Tramper-Stranders GA. Keij FM, et al. Lancet Child Adolesc Health. 2022 Nov;6(11):799-809. doi: 10.1016/S2352-4642(22)00245-0. Epub 2022 Sep 9. Lancet Child Adolesc Health. 2022. PMID: 36088952 Clinical Trial.
A margin of 3% was deemed to indicate non-inferiority, thus if the reinfection rate in the oral amoxicillin-clavulanic acid group was less than 3% higher than that in the intravenous antibiotic group the null hypothesis would be rejected. ...In the intention- …
A margin of 3% was deemed to indicate non-inferiority, thus if the reinfection rate in the oral amoxicillin-clavulanic acid
Identifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial.
Shaikh N, Hoberman A, Shope TR, Jeong JH, Kurs-Lasky M, Martin JM, Bhatnagar S, Muniz GB, Block SL, Andrasko M, Lee MC, Rajakumar K, Wald ER. Shaikh N, et al. JAMA. 2023 Jul 25;330(4):349-358. doi: 10.1001/jama.2023.10854. JAMA. 2023. PMID: 37490085 Free PMC article. Clinical Trial.
The trial was conducted between February 2016 and April 2022 at primary care offices affiliated with 6 US institutions and was designed to evaluate whether symptom burden differed in subgroups defined by nasopharyngeal Streptococcus pneumoniae, Haemophilus influenzae, or Moraxell …
The trial was conducted between February 2016 and April 2022 at primary care offices affiliated with 6 US institutions and was designed to e …
Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial.
Vons C, Barry C, Maitre S, Pautrat K, Leconte M, Costaglioli B, Karoui M, Alves A, Dousset B, Valleur P, Falissard B, Franco D. Vons C, et al. Lancet. 2011 May 7;377(9777):1573-9. doi: 10.1016/S0140-6736(11)60410-8. Lancet. 2011. PMID: 21550483 Clinical Trial.
BACKGROUND: Researchers have suggested that antibiotics could cure acute appendicitis. We assessed the efficacy of amoxicillin plus clavulanic acid by comparison with emergency appendicectomy for treatment of patients with uncomplicated acute appendicitis. .. …
BACKGROUND: Researchers have suggested that antibiotics could cure acute appendicitis. We assessed the efficacy of amoxicillin plus …
Urinary tract infections in adults.
Tan CW, Chlebicki MP. Tan CW, et al. Singapore Med J. 2016 Sep;57(9):485-90. doi: 10.11622/smedj.2016153. Singapore Med J. 2016. PMID: 27662890 Free PMC article.
Escherichia coli remains the predominant uropathogen in acute community-acquired uncomplicated UTIs and amoxicillin-clavulanate is useful as a first-line antibiotic. Family physicians are capable of managing most UTIs if guided by appropriate history, investigations and ap …
Escherichia coli remains the predominant uropathogen in acute community-acquired uncomplicated UTIs and amoxicillin-clavulanate is us …
Stability of Amoxicillin and Clavulanic Acid in Separate Containers for Administration via a Y-Site.
Fawaz S, Merzouk M, Barton S, Nabhani-Gebara S. Fawaz S, et al. Drug Des Devel Ther. 2021 Sep 21;15:3979-3984. doi: 10.2147/DDDT.S310418. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 34584403 Free PMC article.
METHODS: A previously developed and validated stability-indicating HPLC method was used to establish the shelf-life of reconstituted amoxicillin and clavulanic acid when prepared in separate containers. ...CONCLUSION: Amoxicillin and clavulanic
METHODS: A previously developed and validated stability-indicating HPLC method was used to establish the shelf-life of reconstituted amox
Timeliness of administration of amoxicillin-clavulanic acid and meropenem in a large tertiary care centre.
Van Wilder A, Bruyneel L, Decock C, Ten Haaf N, Peetermans WE, Debaveye Y, Vanhaecht K, Spriet I. Van Wilder A, et al. Int J Clin Pharm. 2021 Dec;43(6):1651-1659. doi: 10.1007/s11096-021-01297-0. Epub 2021 Jun 17. Int J Clin Pharm. 2021. PMID: 34138408
Background For amoxicillin-clavulanic acid and meropenem to be effective, concentrations must exceed the minimum inhibitory concentration of infecting pathogens. ...Method All adult hospital stays with at least one amoxicillin-clavulanic acid
Background For amoxicillin-clavulanic acid and meropenem to be effective, concentrations must exceed the minimum inhibi …
High-Dose vs Standard-Dose Amoxicillin Plus Clavulanate for Adults With Acute Sinusitis: A Randomized Clinical Trial.
Gregory J, Huynh B, Tayler B, Korgaonkar-Cherala C, Garrison G, Ata A, Sorum P. Gregory J, et al. JAMA Netw Open. 2021 Mar 1;4(3):e212713. doi: 10.1001/jamanetworkopen.2021.2713. JAMA Netw Open. 2021. PMID: 33755168 Free PMC article. Clinical Trial.
OBJECTIVE: To confirm the previous finding that high-dose amoxicillin plus clavulanate (with double the amount of amoxicillin) may be superior to standard-dose amoxicillin plus clavulanate in adults. ...INTERVENTIONS: Amoxicillin 875 mg with clavulanat …
OBJECTIVE: To confirm the previous finding that high-dose amoxicillin plus clavulanate (with double the amount of amoxicillin) …
Amoxicillin mit Clavulansäure. Standardantibiotikum im allgemeinzahnärztlichen Alltag.
Rostetter C, Schenkel J, Rücker M, Lübbers HT. Rostetter C, et al. Swiss Dent J. 2017;127(7-8):654-655. doi: 10.61872/sdj-2017-07-08-07. Swiss Dent J. 2017. PMID: 28752505 Free article. German.
This script gives a pragmatic advice for general dentists on accurate use of amoxicillin with clavulanic acid considering current literature at acute inflammatory disease. ...Furthermore it is prescribable during pregnancy and lactation. With these advantages …
This script gives a pragmatic advice for general dentists on accurate use of amoxicillin with clavulanic acid consideri …
The safety of amoxicillin and clavulanic acid use during the first trimester of pregnancy.
Daniel S, Doron M, Fishman B, Koren G, Lunenfeld E, Levy A. Daniel S, et al. Br J Clin Pharmacol. 2019 Dec;85(12):2856-2863. doi: 10.1111/bcp.14118. Epub 2019 Dec 3. Br J Clin Pharmacol. 2019. PMID: 31486528 Free PMC article.
AIMS: The goal of the current study was to assess the risk for major congenital malformations following first-trimester exposure to amoxicillin, or amoxicillin and clavulanic acid (ACA). METHODS: A population-based retrospective cohort study was conduc …
AIMS: The goal of the current study was to assess the risk for major congenital malformations following first-trimester exposure to amoxi
6,897 results